CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2834
Family Name Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)phenoxy]benzooxazole Family
No. of Seeds 5 No. of Other Members 15
Family Centroid CFAMM00277471 Functional Category Investigative Drug
Superfamily Leukotriene A-4 hydrolase and Fatty-acid amide hydrolase 1 Binder Superfamily
Class Class 2136

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Nitric oxide synthase, endothelial Inhibitor Acclaim Family 2 15
Substance-P receptor Ligand R 673 Family 2 127
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Fatty-acid amide hydrolase 1 Inhibitor (z)-1-(benzo[d]oxazol-2... 2 27
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Arachidonate 5-lipoxygenase Inhibitor 5-methyl-n-phenylbenzo[d... 5 13
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Sigma non-opioid intracellular receptor 1 ligand 2-[4-(4-cyclo... 2 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
D(4) dopamine receptor ligand SureCN8704964 family 1 2
D(1A) dopamine receptor and D(3) dopamine receptor ligand Lodi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277477 CHEMBL479958 Bioactive Benzoxazole compound, 10a
CFAMM00277478 DNC009560 Investigative Drug JNJ-10392980
CFAMM00277471 DNC009559 Investigative Drug 2-[4-(2-Azepan-1-ylethoxy)phenoxy]benzooxazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26416 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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