| Cousin Family Names | Seeds | Members |
|---|
| 5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... | 14 | 498 |
| Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... | 5 | 644 |
| 5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family | 7 | 460 |
| Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family | 32 | 639 |
| Benzodiazepine receptor Ligand Midazolam Family | 5 | 160 |
| Omega 1 Benzodiazepine receptor Ligand Zaleplon Family | 6 | 589 |
| Toll-like receptor 7 Ligand Imiquimod Family | 3 | 237 |
| Alpha-2A adrenergic receptor Ligand Brimonidine Family | 3 | 6 |
| Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... | 8 | 98 |
| Histamine H1 receptor Ligand Emedastine Family | 5 | 115 |
| Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... | 5 | 60 |
| Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... | 4 | 14 |
| Histamine H1 receptor Ligand Mizolastine Family | 14 | 603 |
| Mast/stem cell growth factor receptor Kit and Vascular endothe... | 6 | 34 |
| Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family | 16 | 135 |
| Metabotropic glutamate receptor 5 Ligand ADX-48621 Family | 15 | 444 |
| C-X-C chemokine receptor type 4 Ligand AMD-070 Family | 12 | 800 |
| Transient receptor potential cation channel subfamily V member... | 15 | 457 |
| Vascular endothelial growth factor Inhibitor PTC299 Family | 6 | 145 |
| Transient receptor potential cation channel subfamily V member... | 6 | 66 |
| Cyclin-dependent kinase 2 Inhibitor Seliciclib Family | 29 | 292 |
| Calcitonin gene-related peptide type 1 receptor Ligand Telcage... | 25 | 124 |
| Fibroblast growth factor receptor 2 and Fibroblast growth fact... | 11 | 86 |
| Cyclin-dependent kinase 4 Inhibitor PD-332991 Family | 13 | 155 |
| Cannabinoid receptor 1 Ligand CP-945598 Family | 18 | 173 |
| Reverse transcriptase Inhibitor Dapivirine Family | 5 | 72 |
| Translocator protein Inhibitor Emapunil Family | 7 | 89 |
| 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... | 14 | 234 |
| Adenosine receptor A1 Ligand SLV320 Family | 6 | 79 |
| Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family | 53 | 580 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 35 | 270 |
| HCV NS4B protein Inhibitor Clemizole Family | 2 | 43 |
| Serine/threonine-protein kinase B-raf Inhibitor GSK2118436 Family | 5 | 19 |
| Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... | 13 | 55 |
| GDC-0349 family | 44 | 77 |
| C-Jun N-terminal kinase Inhibitor CC-930 Family | 2 | 9 |
| PF-4217903 family | 14 | 65 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... | 8 | 55 |
| Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family | 9 | 29 |
| Tryptase Inhibitor Babim Family | 12 | 90 |
| Reverse transcriptase Inhibitor Benzothiadiazines Family | 4 | 21 |
| D(4) dopamine receptor Ligand L-745,870 Family | 30 | 205 |
| CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... | 2 | 7 |
| Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... | 2 | 12 |
| Corticotropin-releasing factor receptor 1 Ligand R121919 Family | 26 | 84 |
| Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family | 3 | 33 |
| Interleukin-1 receptor type 1 and Mitogen-activated protein ki... | 7 | 151 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... | 7 | 72 |
| Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... | 10 | 43 |
| Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... | 31 | 66 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... | 13 | 14 |
| Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... | 18 | 109 |
| Vascular endothelial growth factor receptor 1 and Vascular end... | 6 | 23 |
| Thromboxane-A synthase Inhibitor CGS-13080 Family | 3 | 19 |
| Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... | 14 | 13 |
| Epidermal growth factor receptor Ligand PD-158780 Family | 98 | 89 |
| Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... | 3 | 18 |
| Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... | 2 | 5 |
| Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... | 3 | 16 |
| Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... | 6 | 19 |
| Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... | 5 | 7 |
| Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... | 4 | 9 |
| Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... | 5 | 3 |
| Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... | 3 | 8 |
| Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... | 6 | 5 |
| Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... | 19 | 165 |
| Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family | 14 | 103 |
| Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... | 7 | 12 |
| Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... | 1 | 9 |
| Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... | 8 | 5 |
| Alpha-1A adrenergic receptor Ligand A-315456 Family | 7 | 17 |
| RAC-gamma serine/threonine-protein kinase and Rho-associated p... | 16 | 46 |
| Adenosine receptor A3 and Dual specificity mitogen-activated p... | 5 | 27 |
| Metabotropic glutamate receptor 5 Ligand 2-m-tolyl-1,8-naphthy... | 7 | 11 |
| Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... | 7 | 51 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(4-e... | 2 | 5 |
| Adenosine receptor A3 Ligand 2-(4-nitro-1h-benzo[d]imidazol-2-... | 2 | 12 |
| Delta-type opioid receptor and Kappa-type opioid receptor Liga... | 5 | 45 |
| Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... | 41 | 59 |
| Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... | 8 | 11 |
| Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... | 5 | 13 |
| Mitogen-activated protein kinase kinase kinase 8 and Stromelys... | 6 | 53 |
| Fatty-acid amide hydrolase 1 Inhibitor JNJ-1661010 Family | 3 | 14 |
| Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... | 6 | 3 |
| Aromatase Inhibitor NSC-356781 Family | 3 | 10 |
| Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... | 5 | 4 |
| Histamine H4 receptor Ligand A-943931 Family | 14 | 11 |
| RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... | 219 | 124 |
| Farnesyl pyrophosphate synthase Inhibitor [2-(benzoimidazol-1-... | 2 | 16 |
| Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family | 5 | 6 |
| Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... | 7 | 18 |
| Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... | 17 | 59 |
| Hepatocyte growth factor receptor Ligand 1-benzyl-1h-pyrrolo[3... | 2 | 16 |
| Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family | 27 | 48 |
| Aurora kinase B and Tyrosine-protein kinase Lck Inhibitor CGP-... | 2 | 29 |
| Macrophage metalloelastase Inhibitor Ageladine A Family | 1 | 0 |
| Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... | 3 | 0 |
| Histamine H3 receptor Ligand 4-(2-(phenylamino)ethyl)-1h-imida... | 5 | 16 |
| Type-2 angiotensin II receptor Ligand L-158282 Family | 24 | 58 |
| Type-2 angiotensin II receptor Ligand L-158809 Family | 22 | 136 |
| Proto-oncogene tyrosine-protein kinase Src Inhibitor CGP-62464... | 3 | 10 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... | 4 | 22 |
| Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 6 | 55 |
| Sodium channel protein type 1 subunit alpha and Sodium channel... | 10 | 14 |
| Protein farnesyltransferase subunit beta Inhibitor BMS-316810 ... | 11 | 18 |
| Farnesyltransferase beta subunit, putative and Protein farnesy... | 12 | 4 |
| Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... | 6 | 16 |
| Nitric oxide synthase, inducible and Nitric oxide synthase, br... | 1 | 4 |
| RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... | 20 | 90 |
| Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... | 3 | 13 |
| Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 14 | 4 |
| Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family | 6 | 13 |
| Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... | 7 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... | 1 | 7 |
| Dihydrofolate reductase and Bifunctional dihydrofolate reducta... | 3 | 9 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 4 | 2 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 10 | 3 |
| Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... | 3 | 12 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 4 | 4 |
| Mitogen-activated protein kinase 8 and Mitogen-activated prote... | 2 | 5 |
| cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... | 34 | 11 |
| cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... | 6 | 24 |
| Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... | 7 | 7 |
| Histamine H3 receptor ligand SureCN7853275 family | 2 | 5 |
| Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family | 3 | 6 |
| Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... | 6 | 60 |
| 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 1 | 7 |
| Platelet-activating factor receptor ligand AGN-PC-0750SP family | 4 | 0 |
| 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 7 | 4 |
| Transient receptor potential cation channel subfamily V member... | 1 | 0 |
| Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... | 4 | 12 |
| Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 7 | 10 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 4 | 27 |
| Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... | 1 | 0 |
| Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M82N fa... | 13 | 0 |
| Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M46L fa... | 2 | 7 |
| Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... | 3 | 11 |
| Vascular endothelial growth factor receptor 2 and Mitogen-acti... | 2 | 2 |
| Type-1B angiotensin II receptor ligand SureCN683399 family | 3 | 0 |
| Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... | 4 | 1 |
| Sorbitol dehydrogenase inhibitor SureCN6335187 family | 2 | 6 |
| Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... | 7 | 1 |
| D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... | 13 | 8 |
| Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... | 4 | 4 |
| Prelamin-A/C inhibitor CHEMBL1472945 family | 1 | 32 |
| Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... | 3 | 10 |
| Metabotropic glutamate receptor 1 and Metabotropic glutamate r... | 2 | 2 |
| Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... | 1 | 10 |
| Growth hormone secretagogue receptor type 1 and Dihydrofolate ... | 3 | 6 |
| Coagulation factor X and Trypsin-1 inhibitor 1-(3-carbamimidoy... | 4 | 1 |
| Mitogen-activated protein kinase 13 and Mitogen-activated prot... | 5 | 0 |
| Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 5 | 0 |
| Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... | 3 | 7 |
| Insulin-like growth factor 1 receptor ligand AGN-PC-09QIDN family | 1 | 3 |
| Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... | 15 | 3 |
| Glycogen synthase kinase-3 beta and Dual specificity protein k... | 4 | 5 |
| Corticotropin-releasing factor receptor 1 ligand SureCN6301726... | 4 | 1 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 1 | 2 |
| Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... | 1 | 1 |
| Signal transducer and activator of transcription 6 inhibitor A... | 3 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 1 |
| Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... | 4 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 3 | 5 |
| Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... | 2 | 4 |
| Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... | 2 | 2 |
| Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... | 4 | 14 |
| Aurora kinase A and Cyclin-dependent kinase 1 inhibitor N-[4-[... | 12 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 3 | 11 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 2 | 0 |
| Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... | 2 | 1 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 0 |
| Adenosine deaminase inhibitor AGN-PC-00FYYU family | 4 | 5 |
| Vascular endothelial growth factor receptor 2 ligand urea deri... | 3 | 9 |
| Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 4 ... | 2 | 1 |
| Ribosomal protein S6 kinase alpha-5 inhibitor AGN-PC-075HAD fa... | 2 | 0 |
| Histamine H4 receptor and Histamine H3 receptor ligand (E)-[(3... | 4 | 3 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... | 2 | 0 |
| Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... | 4 | 0 |
| Tyrosine-protein kinase JAK2 and ALK tyrosine kinase receptor ... | 5 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family | 10 | 11 |
| Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... | 11 | 3 |
| Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... | 1 | 0 |
| Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... | 3 | 1 |
| Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... | 3 | 7 |
| Cannabinoid receptor 2 ligand 2-tert-butyl-1-(oxan-4-ylmethyl)... | 8 | 2 |
| Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... | 2 | 2 |
| Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... | 1 | 0 |
| Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... | 10 | 6 |
| Aurora kinase B and Vascular endothelial growth factor recepto... | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 11 | 3 |
| Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... | 1 | 4 |
| Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... | 5 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 3 | 0 |
| TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... | 2 | 2 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 7 | 15 |
| Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... | 4 | 5 |
| Neuropeptide Y receptor type 5 and Cytochrome P450 1A2 ligand ... | 8 | 19 |
| D(4) dopamine receptor and Alpha-1D adrenergic receptor ligand... | 3 | 3 |
| D(4) dopamine receptor and D(3) dopamine receptor ligand AGN-P... | 2 | 0 |
| Protein farnesyltransferase alpha subunit and Protein farnesyl... | 5 | 0 |
| Mitogen-activated protein kinase 14 inhibitor imidazole 81 family | 2 | 1 |
| Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... | 2 | 1 |
| Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... | 1 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family | 8 | 0 |
| High affinity nerve growth factor receptor ligand N-[3-amino-5... | 4 | 10 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family | 16 | 1 |
| Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... | 10 | 0 |
| Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... | 6 | 2 |
| Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... | 3 | 1 |
| Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... | 7 | 0 |
| C-C chemokine receptor type 3 ligand 5-fluoro-1-[1-[3-(4-fluor... | 1 | 2 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta and In... | 3 | 4 |
| Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... | 3 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 5 | 0 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 6 | 2 |
| Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... | 2 | 1 |
| Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[1-... | 5 | 3 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206058 family | 5 | 0 |
| Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206614 family | 2 | 0 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 7 | 4 |
| CGMP-dependent protein kinase inhibitor 1-[2-(4-fluorophenyl)-... | 1 | 4 |
| Corticotropin-releasing factor receptor 1 and Corticotropin-re... | 2 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 7 | 10 |
| Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... | 7 | 2 |
| Corticotropin-releasing factor receptor 1 and Corticotropin-re... | 6 | 3 |
| Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor CDK Inhibito... | 8 | 3 |
| Tyrosine-protein kinase JAK1 and Aurora kinase A inhibitor CHE... | 2 | 0 |
| Serine/threonine-protein kinase ATR and Serine/threonine-prote... | 8 | 10 |
| Protein kinase C theta type and Protein kinase C delta type in... | 9 | 0 |
| CGMP-dependent protein kinase inhibitor SureCN14561191 family | 4 | 0 |
| Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... | 2 | 1 |
| Dipeptidyl peptidase 4 and Seprase inhibitor (1S,5S)-5-[3-(tri... | 1 | 0 |
| Motilin receptor ligand SureCN2004322 family | 2 | 1 |
| Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... | 16 | 0 |
| Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... | 4 | 5 |
| Mitogen-activated protein kinase 8 and Mitogen-activated prote... | 4 | 5 |
| Mitogen-activated protein kinase 8 and Mitogen-activated prote... | 2 | 1 |
| Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... | 4 | 8 |
| Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... | 4 | 1 |
| Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... | 2 | 0 |
| Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(6-morp... | 2 | 0 |
| Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... | 4 | 0 |
| Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... | 2 | 1 |
| Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... | 3 | 1 |
| Cathepsin K inhibitor SureCN4141224 family | 3 | 0 |
| Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... | 5 | 13 |
| Cathepsin K and Cathepsin S inhibitor SureCN4138353 family | 3 | 0 |
| Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... | 2 | 1 |
| Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... | 3 | 0 |
| Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... | 2 | 0 |
| Nociceptin receptor and Potassium voltage-gated channel subfam... | 5 | 2 |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... | 3 | 0 |
| LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... | 4 | 0 |
| Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... | 5 | 1 |
| RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... | 10 | 0 |
| D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... | 2 | 2 |
| Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... | 2 | 3 |
| Corticotropin-releasing factor receptor 1 and Corticotropin-re... | 1 | 0 |
| D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... | 1 | 0 |
| Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... | 1 | 0 |
| Vascular endothelial growth factor receptor 2 and Vascular end... | 1 | 1 |
| Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... | 4 | 1 |
| Histamine H3 receptor ligand AGN-PC-074FK2 family | 4 | 1 |
| Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... | 2 | 0 |
| Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... | 3 | 0 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 1 | 4 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 s... | 3 | 1 |
| 5-hydroxytryptamine receptor 6 ligand 8-(1-pyrrolidin-3-ylpyrr... | 1 | 0 |
| Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... | 4 | 0 |
| Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-a]pyridine der... | 4 | 0 |
| Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ... | 3 | 0 |
| Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... | 12 | 7 |
| Proto-oncogene tyrosine-protein kinase Src and Tyrosine-protei... | 3 | 0 |
| Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... | 3 | 0 |
| Nuclear receptor subfamily 1 group I member 2 ligand AGN-PC-07... | 2 | 13 |
| Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... | 2 | 3 |
| 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... | 4 | 0 |
| Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family | 2 | 0 |
| Cyclin-dependent kinase 2 inhibitor SureCN3549598 family | 3 | 1 |
| Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... | 2 | 0 |
| Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... | 2 | 1 |
| Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inh... | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 and Aurora kinase B inhibit... | 1 | 5 |
| Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... | 4 | 0 |
| 5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family | 3 | 1 |
| Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor ZINC00... | 1 | 0 |
| 5-hydroxytryptamine receptor 2B ligand SureCN1299053 family | 1 | 1 |
| Nociceptin receptor and Potassium voltage-gated channel subfam... | 1 | 0 |
| Cannabinoid receptor 2 ligand AGN-PC-07C4UJ family | 2 | 0 |
| Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... | 14 | 0 |
| LIM domain kinase 1 and LIM domain kinase 2 inhibitor (2S)-N'-... | 9 | 0 |
| LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-[3-(2-hydroxyeth... | 2 | 1 |
| Neuropeptide Y receptor type 5 ligand AGN-PC-01NS1A family | 7 | 0 |
| Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... | 2 | 0 |
| Histamine H3 receptor ligand AGN-PC-074FFM family | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... | 1 | 5 |
| Adenosine receptor A1 ligand AGN-PC-075Q3Q family | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... | 1 | 0 |
| Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor (2S)-2-[[9-p... | 4 | 5 |
| Tyrosine-protein kinase Lck inhibitor N-(2-bromophenyl)imidazo... | 1 | 0 |
| Transient receptor potential cation channel subfamily V member... | 2 | 0 |
Statistics of CFAM Database |
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
|
How to cite our database |
|
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
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Last update by |
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2014.08.29
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