CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2848
Family Name Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenyloctanamido)acetate Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00277774 Functional Category Investigative Drug
Superfamily Cytosolic phospholipase A2 Inhibitor Methyl 2-(2-oxo-8-phenyloctanamido)acetate Superfamily
Class Class 2584

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor Efegatran Family 9 47
Neprilysin Inhibitor Thiorphan Family 41 68
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Penicillin-binding protein 1B Inhibitor N-benzoyl-d-alanine Fa... 1 40
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Disintegrin and metalloproteinase domain-containing protein 17... 8 7
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin K Inhibitor (s)-1-benzylcyclopentyl ... 11 5
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor 3114... 8 9
Peptide deformylase inhibitor (2R)-N-[(2S)-1-(4-fluorophenyl)-... 4 0
Cathepsin K inhibitor [(3R)-4,4-dimethyl-1-phenylpentan-3-yl] ... 7 7
Chymase and Chymotrypsinogen A inhibitor tert-butyl N-[(2S)-1-... 2 7
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 3 4
Dipeptidyl peptidase 4 inhibitor (3R)-4-[(3R)-3-amino-4-(2,4,5... 6 6
N-acylethanolamine-hydrolyzing acid amidase inhibitor 5-phenyl... 2 11
Histone deacetylase 1 and Histone deacetylase 8 inhibitor meth... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 6
Gamma-secretase subunit PEN-2 inhibitor SureCN5966881 family 1 9
Peptide deformylase and Peptide deformylase 1A, chloroplastic/... 1 2
Pol polyprotein inhibitor methyl (2S)-2-[[(2S)-2-[[(2S)-2-[5-[... 1 2
Transcriptional activator protein LuxR inhibitor 3-(3-iodophen... 8 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277776 DNC009598 Investigative Drug tert-Butyl 3-(2-oxo-8-phenyloctanamido)propanoate
CFAMM00277774 DNC009597 Investigative Drug Methyl 2-(2-oxo-8-phenyloctanamido)acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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