CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2869
Family Name Peroxisome proliferator-activated receptor gamma Ligand 2-chloro-5-nitro-n-(pyridin-4-yl)benzamide Family
No. of Seeds 5 No. of Other Members 19
Family Centroid CFAMM00278113 Functional Category Investigative Drug
Superfamily Peroxisome proliferator-activated receptor gamma Ligand 2-chloro-5-nitro-n-(pyridin-4-yl)benzamide Superfamily
Class Class 2589

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Prothrombin Inhibitor Ximelegatran Family 8 157
Smoothened homolog Inhibitor Vismodegib Family 1 19
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
ABC294640 family 5 75
Stress kinase p38 Inhibitor P38 Map Kinase Inhibitor Family 1 3
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
XL-888 family 16 85
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-chlorophenyl)-5-... 2 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Amine oxidase [flavin-containing] B Inhibitor Lazebemide Family 2 13
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Cannabinoid receptor 1 Ligand N-phenyl-5,6-dip-tolylpyrazine-2... 11 26
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 1 2
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Vasopressin V1b receptor ligand 2-[3-(3-chlorophenyl)-1-oxo-7-... 2 12
Nicotinamide phosphoribosyltransferase inhibitor 4-[(7-chloro-... 6 4
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 5 3
Metabotropic glutamate receptor 2 ligand AGN-PC-00A1HD family 2 0
Acetylcholinesterase inhibitor CHEMBL1651131 family 6 9
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Substance-P receptor and Neuromedin-K receptor ligand 2-[3,5-b... 7 0
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 3 0
Dual specificity protein kinase CLK4 and Mitogen-activated pro... 1 1
Seprase and Prolyl endopeptidase inhibitor [(2R)-1-[(2R)-2-[(2... 4 2
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[(4S)-4-(4-chlo... 4 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 17 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Coagulation factor X inhibitor AGN-PC-078Y0T family 11 0
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 3 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-014VFP fa... 1 7
P2X purinoceptor 7 inhibitor 2-chloro-N-[(1-hydroxy-3,3-dimeth... 1 8
Hepatocyte growth factor receptor ligand N-[2-(3-chlorophenyl)... 2 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 1
C-X-C chemokine receptor type 2 ligand 6-chloro-N-(4-fluorophe... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00278125 CHEMBL459470 Bioactive AGN-PC-078VNJ
CFAMM00278114 CHEMBL454876 Bioactive AGN-PC-078VLX
CFAMM00278131 CHEMBL461950 Bioactive AGN-PC-00E1OQ
CFAMM00278128 CHEMBL459674 Bioactive AGN-PC-078VNL
CFAMM00278113 DNC009694 Investigative Drug 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543