CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2870
Family Name Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Family
No. of Seeds 5 No. of Other Members 14
Family Centroid CFAMM00278141 Functional Category Investigative Drug
Superfamily Prostaglandin E2 receptor EP1 subtype Ligand GSK-345931A Superfamily
Class Class 2048

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 1 7
Insulin-like growth factor-binding protein 4 and Insulin-like ... 4 44
Leukotriene B4 receptor 1 ligand SureCN8987110 family 8 20
Glutamate receptor ionotropic, NMDA 1 ligand (3S)-3-[2-[4-(ami... 1 1
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 7 5
Insulin-like growth factor-binding protein 3 inhibitor (1E)-1-... 2 0
Prostaglandin E2 receptor EP1 subtype and Thromboxane A2 recep... 1 0
Cysteinyl leukotriene receptor 1 ligand 6-bromo-4-oxo-3-(quino... 3 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 6 5
Prostaglandin E2 receptor EP1 subtype and Prostaglandin E2 rec... 3 4


External ID

Functional Category

Molecule Name

CFAMM00278145 CHEMBL514574 Bioactive 6-[2-[5-chloro-2-[(2,4-difluorophenyl)methoxy]phenyl]phenyl]pyridine-2-carboxylic acid
CFAMM00278135 CHEMBL515981 Bioactive 6-[2-(5-chloro-2-phenylmethoxyphenyl)phenyl]pyridine-2-carboxylic acid
CFAMM00278139 CHEMBL457142 Bioactive 6-[2-[5-chloro-2-[(4-fluorophenyl)methoxy]phenyl]phenyl]pyridine-2-carboxylic acid
CFAMM00278148 CHEMBL234940 Bioactive GW848687X
CFAMM00278141 DNC009697 Investigative Drug GSK-345931A

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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