CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2874
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-phenyl-5-sulfamoyl-1h-indole-2-carboxamide Family
No. of Seeds 10 No. of Other Members 27
Family Centroid CFAMM00278197 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-phenyl-5-sulfamoyl-1h-indole-2-carboxamide Superfamily
Class Class 952

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 1 11
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 4 21
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 6 6
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3-fluo... 6 4
Hepatocyte growth factor receptor and Protein-tyrosine kinase ... 2 15
Pol polyprotein and Reverse transcriptase/RNaseH inhibitor CSI... 1 5
Tyrosine-protein kinase Yes and Proto-oncogene tyrosine-protei... 7 18
Carbonic anhydrase 2 and Carbonic anhydrase inhibitor 3-(3-chl... 6 0


External ID

Functional Category

Molecule Name

CFAMM00278179 CHEMBL468094 Bioactive AGN-PC-0726SY
CFAMM00278192 CHEMBL262628 Bioactive 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide
CFAMM00278170 CHEMBL468294 Bioactive AGN-PC-0726WA
CFAMM00278207 CHEMBL466832 Bioactive AGN-PC-0726SW
CFAMM00278167 CHEMBL466234 Bioactive AGN-PC-0726WG
CFAMM00278166 CHEMBL468945 Bioactive AGN-PC-0726US
CFAMM00278181 CHEMBL501294 Bioactive AGN-PC-0726UW
CFAMM00278165 CHEMBL468946 Bioactive AGN-PC-0726WI
CFAMM00278180 CHEMBL469126 Bioactive AGN-PC-0726UY
CFAMM00278197 DNC009703 Investigative Drug 3-phenyl-5-sulfamoyl-1H-indole-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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