CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2876
Family Name Protein kinase C delta type and Protein kinase C alpha type Inhibitor Dihexan-3-yl 5-(hydroxymethyl)isophthalate Family
No. of Seeds 4 No. of Other Members 105
Family Centroid CFAMM00278241 Functional Category Investigative Drug with Natural Product
Superfamily Protein kinase C delta type and Protein kinase C alpha type Inhibitor Dihexan-3-yl 5-(hydroxymethyl)isophthalate Superfamily
Class Class 1012

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family 1 42
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Acetyl-CoA carboxylase 2 Inhibitor Soraphen A Family 2 80
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Neutrophil elastase Inhibitor E-6-o-p-methoxycinnamoyl Scandos... 2 68
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
Protein kinase C alpha type inhibitor [(4E)-4-[(4-fluorophenyl... 4 66
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Protein kinase C delta type and Protein kinase C beta type inh... 3 9
Protein kinase C delta type and Protein kinase C alpha type in... 1 10
Protein kinase C alpha type inhibitor [(4E)-4-[(4-chloro-3-flu... 5 7
Protein kinase C alpha type inhibitor [(4E)-4-[(3-bromo-4-fluo... 3 5
Cholinesterase inhibitor [(3R,3aR,6S,6aR)-6-(ethylcarbamoyloxy... 2 4
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
3-(4-hydroxy-6-methyl-2-oxopyran-3-yl)-3H-2-benzofuran-1-one N... 2 2
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1


External ID

Functional Category

Molecule Name

CFAMM00278249 CHEMBL382784 Bioactive [(4Z)-2-(hydroxymethyl)-4-[5-methyl-3-(2-methylpropyl)hexylidene]-5-oxooxolan-2-yl]methyl benzoate
CFAMM00278217 CHEMBL110256 Bioactive AC1NV751
CFAMM00278242 DNC009707 Investigative Drug diheptan-3-yl 5-(hydroxymethyl)isophthalate
CFAMM00278241 DNC009706 Investigative Drug dihexan-3-yl 5-(hydroxymethyl)isophthalate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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