CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2881
Family Name Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1h-indole-3-carboxylate Family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00278523 Functional Category Investigative Drug with Natural Product
Superfamily Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1h-indole-3-carboxylate Superfamily
Class Class 1259

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
Survival motor neuron protein inhibitor CHEMBL1581561 family 1 3
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 12
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 9 6
5-hydroxytryptamine receptor 3A ligand 3-methyl-N-[7-[[3-methy... 2 0
Growth hormone secretagogue receptor type 1 ligand SureCN62436... 8 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 0
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Neutrophil elastase inhibitor AGN-PC-076VCN family 3 25
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C19 ... 1 4
Acetyl-CoA carboxylase 2 and Acetyl-Coenzyme A carboxylase 2 i... 1 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 2
2-amino-7,7-dimethyl-5,8-dihydropyrano[4,3-b]pyridine-3-carbox... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00278528 CHEMBL371144 Bioactive AGN-PC-005M1W
CFAMM00278531 DNC009728 Investigative Drug Methyl 2-(Diallylamino)-1H-indole-3-carboxylate
CFAMM00278523 DNC009727 Investigative Drug Methyl 2-(Benzylamino)-1H-indole-3-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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