CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2883
Family Name Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298 Family
No. of Seeds 53 No. of Other Members 320
Family Centroid CFAMM00278747 Functional Category Investigative Drug with Natural Product
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298 Superfamily
Class Class 2593

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Adenosine receptor A2a Ligand KW-6002 Family 18 195
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 12 197
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Integrin beta-3 Inhibitor L-756568 Family 8 59
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Alpha-1A adrenergic receptor Ligand A-131701 Family 16 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand WIN-5... 12 52
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
D(2) dopamine receptor Ligand SLV-314 Family 19 69
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Reverse transcriptase Inhibitor Atevirdine Family 4 55
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 28 24
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 14
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Lysine--tRNA ligase and Dual specificity protein kinase CLK4 i... 4 27
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Disintegrin and metalloproteinase domain-containing protein 17... 2 1
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Somatostatin receptor type 2 ligand tert-butyl (2S)-6-amino-2-... 2 15
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 21 11
Neuropeptide Y receptor type 5 ligand SureCN5771669 family 2 3
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
D(2) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 6 22
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[4-(5-ethyl-1,2,4... 25 61
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Translocator protein inhibitor N-(4-methoxyphenyl)-N,3-dimethy... 2 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 11
Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[3-fluoro-4-(5-ph... 10 2
Histamine H3 receptor ligand N-[(2R)-1-[4-[3-[4-[5-(cyclopenty... 27 2
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Histamine H3 receptor ligand SureCN7251693 family 3 1
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Serine/threonine-protein kinase Chk2 inhibitor SureCN3919556 f... 4 8
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 3 0
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 3 4
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor 3-... 4 8
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
D(2) dopamine receptor and D(3) dopamine receptor ligand N-[3-... 7 3
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Adenosine receptor A2b and Adenosine receptor A1 ligand (8Z)-8... 3 33
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 3 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Adenosine receptor A2b ligand 2-[5-(2,6-dioxo-1,3-dipropyl-7H-... 1 0
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 8 6
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Substance-P receptor ligand (3R)-4-[3,5-bis(trifluoromethyl)be... 2 3
Smoothened homolog inhibitor N-[3-(1H-benzimidazol-2-yl)phenyl... 2 1
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
Sonic hedgehog protein inhibitor 3-methoxy-1-methyl-4-oxo-5-ph... 5 3
Microsomal triglyceride transfer protein large subunit inhibit... 9 0
Mu-type opioid receptor and Mu-type opioid receptor ligand (3S... 6 2
Substance-P receptor ligand AGN-PC-01VLKE family 9 11
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Beta-2 adrenergic receptor ligand SureCN4598646 family 7 7
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Disintegrin and metalloproteinase domain-containing protein 17... 5 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
C-C chemokine receptor type 5 ligand N-methyl-4-[6-methyl-5-[[... 2 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Disintegrin and metalloproteinase domain-containing protein 17... 5 0
Collagenase 3 inhibitor 5-[4-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Adenosine receptor A2b ligand 6-[4-[1-[4-(6-chloro-1,3-benzoth... 1 1
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 1
Platelet-activating factor receptor ligand N,N-dimethyl-6-phen... 12 18
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Mu-type opioid receptor ligand MITRAGYNINE family 2 8
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 1
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 16 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiest... 7 0
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(3,4... 1 8
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 1
Vasopressin V2 receptor ligand SureCN4400636 family 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,... 6 15
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 2 0
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 0
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 2 0
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Cholecystokinin receptor type A ligand AGN-PC-077KXF family 2 0
Adenosine receptor A2b and Adenosine receptor A2a ligand 1-eth... 5 2
Adenosine receptor A2b and Adenosine receptor A2a ligand 7-hyd... 1 8
Adenosine receptor A1 and Adenosine receptor A2b ligand N-[2-[... 2 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07C5JC family 1 3
P2Y purinoceptor 12 inhibitor (4S)-4-[[4-[(1-acetylpiperidin-4... 58 15
Adenosine receptor A3 and Adenosine receptor A2a ligand 9-prop... 1 0
Bombesin receptor subtype-3 ligand 2-[[(E)-furan-2-ylmethylide... 2 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
P2X purinoceptor 7 inhibitor (7R)-1-[(3,4-difluorophenyl)methy... 1 0
Orexin receptor type 1 and Adenosine receptor A2a ligand 1-(2-... 2 2
Potassium voltage-gated channel subfamily A member 5 ligand AG... 1 0
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 1 1
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 1
Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-0763... 1 1
Adenosine receptor A2b and Adenosine receptor A2a ligand 6-(fu... 2 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 0
Amino Acids and Derivatives Metabolite Flazine Family 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00278670 CHEMBL190034 Bioactive 6-(4-methoxyphenyl)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278835 CHEMBL201750 Bioactive N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-3-methoxyphenoxy]acetamide
CFAMM00278841 CHEMBL192941 Bioactive 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-6-phenyl-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278918 CHEMBL412112 Bioactive 3-methyl-6-[4-[2-oxo-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]phenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278611 CHEMBL201145 Bioactive N-(4-bromophenyl)-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278721 CHEMBL201239 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-[4-(trifluoromethoxy)phenyl]acetamide
CFAMM00278574 CHEMBL377485 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-phenylmethoxyphenyl)acetamide
CFAMM00278669 CHEMBL382135 Bioactive N-(4-cyanophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278924 CHEMBL203037 Bioactive N-(6-methoxypyridin-3-yl)-2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278661 CHEMBL201773 Bioactive N-benzyl-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278740 CHEMBL382764 Bioactive N-(4-chlorophenyl)-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278889 CHEMBL201028 Bioactive N-[(4-chlorophenyl)methyl]-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]propanamide
CFAMM00278766 CHEMBL201493 Bioactive N-(4-bromophenyl)-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]butanamide
CFAMM00278827 CHEMBL199486 Bioactive 2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)propanamide
CFAMM00278833 CHEMBL381091 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)butanamide
CFAMM00278573 CHEMBL202665 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylacetamide
CFAMM00278895 CHEMBL190525 Bioactive 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-6-(4-methylphenyl)-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278739 CHEMBL294223 Bioactive 6-[4-[2-(4,4-diphenylpiperidin-1-yl)-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278852 CHEMBL192119 Bioactive 3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-6-phenyl-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278666 CHEMBL201008 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-[4-(pyrrolidin-1-ylsulfonylmethyl)phenyl]acetamide
CFAMM00278745 CHEMBL202767 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-methoxyphenyl)propanamide
CFAMM00278819 CHEMBL260693 Bioactive 6-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278894 CHEMBL201157 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-2-methyl-N-phenylpropanamide
CFAMM00278922 CHEMBL370378 Bioactive N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278615 CHEMBL201281 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
CFAMM00278579 CHEMBL198338 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylbutanamide
CFAMM00278778 CHEMBL456125 Bioactive N-(4-bromophenyl)-2-[4-(7-hydroxy-2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278594 CHEMBL199446 Bioactive 2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
CFAMM00278805 CHEMBL199862 Bioactive 2-[4-[1,3-bis(cyclopropylmethyl)-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl]phenoxy]-N-phenylacetamide
CFAMM00278744 CHEMBL202766 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylpropanamide
CFAMM00278818 CHEMBL260692 Bioactive 1,3-dimethyl-6-[4-[1-[4-(4-methylphenyl)piperazin-1-yl]-1-oxopropan-2-yl]oxyphenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278614 CHEMBL372148 Bioactive 2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-phenylphenyl)acetamide
CFAMM00278711 CHEMBL201127 Bioactive N-(4-fluorophenyl)-2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278724 CHEMBL409514 Bioactive 6-[4-[2-(4-benzylpiperazin-1-yl)-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278750 CHEMBL381538 Bioactive N-(4-fluorophenyl)-2-[4-(3-methyl-2,4-dioxo-1-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278824 CHEMBL200052 Bioactive N-(4-iodophenyl)-2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278850 CHEMBL259857 Bioactive 3-methyl-6-[4-[2-oxo-2-(4-phenylpiperidin-1-yl)ethoxy]phenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278791 CHEMBL370588 Bioactive N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]propanamide
CFAMM00278599 CHEMBL381214 Bioactive 2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-nitrophenyl)acetamide
CFAMM00278856 CHEMBL1170167 Bioactive N-(4-bromophenyl)-2-[4-(2,4-dioxo-3-propyl-1,5-dihydropyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278823 CHEMBL260051 Bioactive 6-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278863 CHEMBL380847 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)propanamide
CFAMM00278716 CHEMBL201128 Bioactive 2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)-2-methylpropanamide
CFAMM00278816 CHEMBL201721 Bioactive 2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylacetamide
CFAMM00278842 CHEMBL506179 Bioactive 6-[4-[2-(4-benzylpiperazin-1-yl)-2-oxoethoxy]phenyl]-7-hydroxy-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
CFAMM00278584 CHEMBL439868 Bioactive N-(4-acetylphenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278968 CHEMBL203413 Bioactive 2-[4-(1,3-diethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylacetamide
CFAMM00278796 CHEMBL199611 Bioactive 2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylpropanamide
CFAMM00278855 CHEMBL1170166 Bioactive 2-[4-(2,4-dioxo-3-propyl-1,5-dihydropyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
CFAMM00278869 CHEMBL203305 Bioactive N-[(4-chlorophenyl)methyl]-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278947 CHEMBL201749 Bioactive N-(4-tert-butylphenyl)-2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
CFAMM00278747 DNC009735 Investigative Drug SB-298

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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