CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Coagulation factor X Inhibitor SN429 Family
No. of Seeds 23 No. of Other Members 100
Family Centroid CFAMM00186526 Functional Category Investigative Drug
Superfamily Coagulation factor X Inhibitor SN429 Superfamily
Class Class 1276

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Coagulation factor X and Trypsin-1 inhibitor SureCN3836037 family 5 4
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-075TBZ family 2 2
Coagulation factor X and Trypsin-1 inhibitor 3-(3-carbamimidoy... 1 0
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 2 2
Coagulation factor X inhibitor 2-(6-chloronaphthalen-2-yl)-5-m... 2 0
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor SureCN8168539 family 3 0
Coagulation factor X inhibitor SureCN8165148 family 4 0
Coagulation factor X inhibitor AGN-PC-0749JT family 1 0
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Coagulation factor X inhibitor DPC 423 derivative, 8 family 1 2
Progesterone receptor ligand AGN-PC-00OK6G family 7 8
Coagulation factor X inhibitor (Z)-3-(3-carbamimidoylphenyl)-2... 2 2
Coagulation factor X inhibitor AGN-PC-046QCP family 2 0
Coagulation factor X inhibitor SureCN5254091 family 5 0
Coagulation factor X inhibitor 3kqc family 1 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
P2X purinoceptor 7 inhibitor SureCN1194877 family 1 6
Ketohexokinase inhibitor 3-carbamimidoyl-N-(3-ethyl-1-phenylin... 1 0


External ID

Functional Category

Molecule Name

CFAMM00186494 CHEMBL134736 Bioactive SureCN14542915
CFAMM00186523 CHEMBL154680 Bioactive SureCN13550922
CFAMM00186487 CHEMBL440733 Bioactive 2-(3-carbamimidoylphenyl)-5-methyl-N-[4-(2-methylsulfonylphenyl)phenyl]pyrazole-3-carboxamide
CFAMM00186550 CHEMBL246323 Bioactive DPC 423 derivative, 5
CFAMM00186577 CHEMBL347307 Bioactive 2-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-methylpyrazole-3-carboxamide
CFAMM00186543 CHEMBL348441 Bioactive AGN-PC-075RO4
CFAMM00186556 CHEMBL422351 Bioactive 2-[3-(aminomethyl)phenyl]-N-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-5-methylpyrazole-3-carboxamide
CFAMM00186514 CHEMBL154572 Bioactive 2-[3-(aminomethyl)phenyl]-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-methylpyrazole-3-carboxamide
CFAMM00186528 CHEMBL152281 Bioactive AGN-PC-075TEJ
CFAMM00186542 CHEMBL358835 Bioactive 2-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00186472 CHEMBL154238 Bioactive 2-(3-carbamimidoylphenyl)-N-[4-(2-methylsulfonylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00186465 CHEMBL154504 Bioactive SureCN7746996
CFAMM00186490 CHEMBL148944 Bioactive 2-[2-(aminomethyl)phenyl]-N-[4-(2-sulfamoylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00186532 CHEMBL151939 Bioactive SureCN14318599
CFAMM00186470 CHEMBL559015 Bioactive 2-[3-(aminomethyl)phenyl]-N-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide;hydrochloride
CFAMM00186463 CHEMBL422688 Bioactive 2-(3-carbamimidoylphenyl)-N-[2-fluoro-4-(2-methylsulfonylphenyl)phenyl]-5-methylpyrazole-3-carboxamide
CFAMM00186552 CHEMBL347846 Bioactive AGN-PC-00PBIF
CFAMM00186517 CHEMBL601216 Bioactive AGN-PC-07RB5D
CFAMM00186572 CHEMBL347931 Bioactive AGN-PC-075TFL
CFAMM00186586 CHEMBL41982 Bioactive SureCN8168536
CFAMM00186516 CHEMBL152854 Bioactive AGN-PC-075TE8
CFAMM00186493 DNC000574 Investigative Drug DPC 423
CFAMM00186526 DNC001346 Investigative Drug SN429

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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