CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2916
Family Name Histone deacetylase 1 Inhibitor N-hydroxy-8-(2-methoxyphenyl)-8-oxooctanamide Family
No. of Seeds 2 No. of Other Members 14
Family Centroid CFAMM00279813 Functional Category Investigative Drug with Natural Product
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Binder Superfamily
Class Class 2041

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Dihydroorotate dehydrogenase Inhibitor Salicylhydroxamic Acid ... 2 8
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3 89
Galectin-3 Inhibitor 2,3,5,6-tetrafluoro-4-methoxy-benzamide F... 1 0
Poly [ADP-ribose] polymerase 1 Inhibitor 3-methoxybenzamide Fa... 2 23
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Steryl-sulfatase Inhibitor Sulfamic Acid 4-(3-methoxy-benzoyl)... 5 24
Scytalone dehydratase Inhibitor 5-fluoro-2-hydroxy-n-isopropyl... 3 14
Steryl-sulfatase Inhibitor Sulfamic Acid 2-nonyl-4-oxo-4h-chro... 4 68
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Interstitial collagenase Inhibitor N-hydroxy-4-(4-methoxy-phen... 6 4
Interstitial collagenase Inhibitor N-hydroxycarbamoylmethyl-4-... 5 24
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Neutrophil elastase and Urokinase-type plasminogen activator I... 1 3
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Amine oxidase [flavin-containing] B Inhibitor (s)(+)-7-fluoro-... 11 11
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 2-(3-c... 5 72
D(2) dopamine receptor Ligand Epidepride Family 31 66
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
Trace amine-associated receptor 1 ligand SureCN13886619 family 1 1
Stromelysin-1 inhibitor N-hydroxy-2-[3-[4-(4-methoxyphenyl)phe... 2 1
Putative NP ZINC02127056 Family 4 1
2-methyl-2H-chromene-3-carbaldehyde NP 2-methyl-2h-chromene-3-... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00279808 CHEMBL1405973 Bioactive exalamide
CFAMM00279813 DNC009834 Investigative Drug N-hydroxy-8-(2-methoxyphenyl)-8-oxooctanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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