CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2933
Family Name Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(diethylamino)phenyl)-2-nitrobenzamide Family
No. of Seeds 2 No. of Other Members 17
Family Centroid CFAMM00280371 Functional Category Investigative Drug with Natural Product
Superfamily Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(diethylamino)phenyl)-2-nitrobenzamide Superfamily
Class Class 311

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Androgen receptor ligand aniline derivative Flutamide Family 3 9
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Voltage-gated sodium channel Ligand Oxcarbazepine Family 1 4
4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Serum albumin Inhibitor Ebselen Family 3 62
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Dual specificity mitogen-activated protein kinase kinase Inhib... 5 13
Motilin receptor Ligand GSK962040 Family 30 457
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Dual specificity mitogen-activated protein kinase kinase Inhib... 8 4
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
MO15-related protein kinase Pfmrk Inhibitor 5-nitro-1h-indole-... 1 4
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Liver carboxylesterase 1 Inhibitor 1-(4-nitro-phenyl)-2-phenyl... 2 7
Transient receptor potential cation channel subfamily V member... 6 33
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 1 9
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Transient receptor potential cation channel subfamily V member... 1 5
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Benz... 3 12
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Progesterone receptor and Androgen receptor ligand AGN-PC-080P... 4 27
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 2 4
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Transient receptor potential cation channel subfamily V member... 1 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 19
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 11
Chitin synthase 1 inhibitor AC1O53V7 family 9 0
Microbial collagenase inhibitor AGN-PC-074HD0 family 2 3
Vascular endothelial growth factor receptor 2 ligand SureCN578... 1 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Histone deacetylase 1 inhibitor AGN-PC-07ZGOT family 2 1
Progesterone receptor ligand SureCN3525721 family 1 2
Caspase-3 inhibitor Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1... 2 3
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 6-oxo-9-(2-oxo-... 1 0
Telomerase reverse transcriptase inhibitor AGN-PC-07ZBGW family 2 0
Proteinase-activated receptor 1 ligand 2-bromo-N-[3-(butanoyla... 4 0
D-alanyl-D-alanine carboxypeptidase and Penicillin-binding pro... 1 0
Lysophosphatidic acid receptor 3 and Microtubule-associated pr... 1 1
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00280371 DNC009892 Investigative Drug N-(4-(diethylamino)phenyl)-2-nitrobenzamide
CFAMM00280370 DNC009896 Investigative Drug N-(2,4-dimethylphenyl)-2-nitrobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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