CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2945
Family Name Aromatase Inhibitor NSC-122427 Family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00280546 Functional Category Investigative Drug
Superfamily Aromatase and Thyroid hormone receptor beta Binder Superfamily
Class Class 2440

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Proto-oncogene tyrosine-protein kinase Src Inhibitor Malonic A... 1 34
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Amyloid beta A4 protein Inhibitor 2,5-bis(4-methoxyphenyl)thio... 3 31
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Prostaglandin G/H synthase 1 Inhibitor Acetic Acid 2-heptylsel... 1 14
Androgen receptor Ligand Palodesangren E Family 12 43
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 12 10
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
DNA-(apurinic or apyrimidinic site) lyase and Phospholipase A2... 1 4
Progesterone receptor ligand 6-(5-chlorothiophen-2-yl)chromen-... 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor propan... 3 5
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
dimethylchromen-2-one NP 4-(chloromethyl)-6,7-dimethyl-2h-chro... 5 2
3-pentyl-5-(phenoxymethyl)oxolan-2-one NP ZINC02116245 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00280546 DNC009932 Investigative Drug NSC-122427

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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