CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2956
Family Name 72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhibitor 2-(biphenyl-4-ylsulfonyl)n-hydroxybenzamide Family
No. of Seeds 7 No. of Other Members 8
Family Centroid CFAMM00280717 Functional Category Investigative Drug
Superfamily 72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhibitor 2-(biphenyl-4-ylsulfonyl)n-hydroxybenzamide Superfamily
Class Class 2219

Cousin Family NamesSeedsMembers
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase I... 2 2
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-be... 6 15
Aminopeptidase N Inhibitor N-hydroxy-2-(naphthalen-2-ylsulfany... 1 2
Sodium/hydrogen exchanger 1 and Sodium/hydrogen exchanger 3 In... 9 91
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Saccha... 2 13
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Acetylcholinesterase and Butyrylcholinesterase inhibitor N-[2-... 3 7
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-044L... 6 7
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Interstitial collagenase inhibitor AGN-PC-075XLO family 2 1
Amine oxidase [flavin-containing] A inhibitor N,7-dimethyl-9,1... 3 5
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-2-... 2 0
Collagenase 3 and Macrophage metalloelastase inhibitor N-hydro... 1 0
Collagenase 3 and Interstitial collagenase inhibitor N-hydroxy... 1 2


External ID

Functional Category

Molecule Name

CFAMM00280720 CHEMBL1083416 Bioactive SureCN3157651
CFAMM00280711 CHEMBL34206 Bioactive 2-[(4-benzoylphenyl)sulfonylmethyl]-N-hydroxy-5-phenylpentanamide
CFAMM00280718 CHEMBL574370 Bioactive AGN-PC-076LVZ
CFAMM00280724 CHEMBL1086507 Bioactive SureCN3157709
CFAMM00280723 CHEMBL1082467 Bioactive SureCN3159119
CFAMM00280722 CHEMBL574605 Bioactive AGN-PC-076M2B
CFAMM00280717 DNC009957 Investigative Drug 2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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