CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2958
Family Name Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic Acid Family
No. of Seeds 4 No. of Other Members 43
Family Centroid CFAMM00280809 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic Acid Superfamily
Class Class 2618

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
CPI-613 family 4 35
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Calcium-activated potassium channel subunit alpha-1 Ligand Tri... 1 10
Aldo-keto reductase family 1 member C3 Inhibitor 2,2-dibenzylc... 2 15
Prostaglandin G/H synthase 1 Inhibitor 2-(3'-ethylsulfanyl-bip... 1 4
Trypsin-1 and Prothrombin inhibitor (3S,3aR,6aS)-3-benzyl-3,3a... 2 23
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (4R,... 2 15
Free fatty acid receptor 1 and Free fatty acid receptor 4 liga... 1 7
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor [(1S... 2 9
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 9
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Leukotriene B4 receptor 1 ligand 2-[1-hydroxy-3-[(E)-3-hydroxy... 3 1
Free fatty acid receptor 1 ligand AGN-PC-0CCG7G family 1 2
Peroxisome proliferator-activated receptor gamma ligand SureCN... 3 3
Beta-lactamase inhibitor CHEMBL1358094 family 1 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Sodium-dependent dopamine transporter inhibitor AGN-PC-074TA8 ... 2 5
Carboxylic Acids and Derivatives Metabolite 3-Acetoxy-3-methyl... 2 0
Putative NP ZINC06763537 Family 6 4
NP 3,3,5,5-tetramethyl-6-(phenylethynyl)dihydro-2h-pyran-2,4(3... 6 3
Putative NP ZINC02930279 Family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00280809 DNC009966 Investigative Drug 5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid
CFAMM00280812 DNC009961 Investigative Drug 5-(biphenyl-4-yl)-3-methoxypentanoic acid
CFAMM00280811 DNC009960 Investigative Drug (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid
CFAMM00280810 DNC009967 Investigative Drug 5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48700 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543