CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2967
Family Name Adenosine receptor A3 Ligand 2-phenyl-2h-pyrazolo[4,3-d]pyrimidin-7(6h)-one Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00280893 Functional Category Investigative Drug
Superfamily Adenosine receptor A3 Ligand 2-phenyl-2h-pyrazolo[4,3-d]pyrimidin-7(6h)-one Superfamily
Class Class 1032

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Cyclin-dependent kinase 2 Inhibitor AT7519 Family 2 14
Poly [ADP-ribose] polymerase 1 Inhibitor MK-4827 Family 8 43
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Cyclin-dependent kinase 2 Inhibitor N-phenyl-1h-pyrazole-3-car... 1 1
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
Hepatocyte growth factor receptor ligand 9-[[3-methoxypropyl(m... 17 2
Cannabinoid receptor 1 ligand N-[1-[[(1R)-1-[4-(3-chloroindazo... 10 0
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(2-meth... 7 9
Histamine H3 receptor ligand N-methyl-N-[(3R)-1-propan-2-ylpyr... 3 1
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Hepatocyte growth factor receptor ligand 5-(3-methyl-1,2-thiaz... 5 2
Cannabinoid receptor 1 and Cytochrome P450 3A4 ligand N-(oxan-... 2 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 1
Tyrosine-protein kinase receptor TYRO3 ligand 3-amino-6-(1H-in... 2 3
Vascular endothelial growth factor receptor 2 and Vascular end... 5 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00280895 CHEMBL583794 Bioactive 5-methyl-2-(4-methylphenyl)-4H-pyrazolo[4,3-d]pyrimidin-7-one
CFAMM00280893 DNC009982 Investigative Drug 2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27520 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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