CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2976
Family Name Sphingosine kinase 2 Inhibitor (r)-2-amino-4-hydroxy-n-(4-octylphenyl)butanamide Family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00281015 Functional Category Investigative Drug
Superfamily Sphingosine kinase 2 Binder Superfamily
Class Class 2103

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Proto-oncogene tyrosine-protein kinase Src Inhibitor ISO24 Family 3 9
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Sphingosine kinase 2 Inhibitor (r)-2-amino-3-(4-octylphenylami... 1 16
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Protein kinase C alpha type inhibitor 5-[3,5-bis(trifluorometh... 3 0
Protein kinase C delta type and Protein kinase C alpha type in... 5 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Ectonucleotide pyrophosphatase/phosphodiesterase family member... 1 0
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Excitatory amino acid transporter 2 and Excitatory amino acid ... 1 14
Sphingosine 1-phosphate receptor 5 and Sphingosine 1-phosphate... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00281012 DNC010028 Investigative Drug (S)-2-amino-6-hydroxy-N-(4-octylphenyl)hexanamide
CFAMM00281015 DNC010026 Investigative Drug (R)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide
CFAMM00281014 DNC010027 Investigative Drug (S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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