CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2988
Family Name Indoleamine 2,3-dioxygenase 1 Inhibitor 4-aminonaphthalen-1-ol Family
No. of Seeds 2 No. of Other Members 34
Family Centroid CFAMM00281430 Functional Category Investigative Drug with Human Metabolite
Superfamily Indoleamine 2,3-dioxygenase 1 and Insulin receptor Binder Superfamily
Class Class 2428

Cousin Family NamesSeedsMembers
Bcl-2 Inhibitor family 1 11
DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenes... 1 19
D(2) dopamine receptor Ligand 2,3-dihydro-1h-indol-5-ol Family 1 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4'-am... 3 17
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(ethylamino)naphthal... 10 13
Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family 5 12
Aromatase Inhibitor 3,5-dihydroxyl-4'-amino-trans-stilbene Family 1 1
Insulin receptor and Insulin-like growth factor 1 receptor Lig... 1 0
Fatty acid-binding protein Inhibitor 1-anilinonaphthalene-8-su... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Transporter and Sodium-dependent dopamine transporter inhibito... 1 1
Sodium-dependent serotonin transporter inhibitor 2-[2-[(dimeth... 3 3
Arachidonate 5-lipoxygenase inhibitor AGN-PC-0752DJ family 1 2
Estradiol 17-beta-dehydrogenase 1 and Estradiol 17-beta-dehydr... 3 10
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 2
Estradiol 17-beta-dehydrogenase 2 and Estradiol 17-beta-dehydr... 1 2
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-075CPV ... 2 3
Benzene and Substituted Derivatives Metabolite 4-Hydroxy-2,6-d... 1 3


External ID

Functional Category

Molecule Name

CFAMM00281411 DNC010105 Investigative Drug 4-methoxynaphthalen-1-amine
CFAMM00281430 DNC010092 Investigative Drug 4-aminonaphthalen-1-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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