CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2989
Family Name Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol Family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00281440 Functional Category Investigative Drug
Superfamily Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol Superfamily
Class Class 2231

Cousin Family NamesSeedsMembers
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
TS-071 family 8 36
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Estrogen receptor beta Ligand 1-chloro-6-(4-hydroxyphenyl)-2-n... 12 23
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oestrogen receptor and Estrogen receptor beta Ligand 1-bromo-6... 3 4
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Tyrosinase Inhibitor 4-adamantyl Resorcinol Family 1 1
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
Estrogen receptor beta and Estrogen receptor ligand (4Z)-2-flu... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Androgen receptor and Progesterone receptor ligand diarylpheno... 1 1
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-[3,... 4 0
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor 2,2-d... 1 0
Acenes Metabolite 2-Methyl-1,4-naphthalenediol bis(dihydrogen ... 2 2
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00281443 CHEMBL85000 Bioactive 2-benzylnaphthalen-1-ol
CFAMM00281440 DNC010093 Investigative Drug naphthalene-1,4-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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