CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2990
Family Name Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(ethylamino)naphthalen-1-ol Family
No. of Seeds 10 No. of Other Members 13
Family Centroid CFAMM00281464 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Indoleamine 2,3-dioxygenase 1 and Insulin receptor Binder Superfamily
Class Class 2428

Cousin Family NamesSeedsMembers
Opioid receptor ligand opiate Levorphanol Family 18 537
Acetylcholinesterase Inhibitor Edrophonium Family 7 40
Oestrogen receptor and Estrogen receptor beta Ligand 2-(4-hydr... 10 17
D(2) dopamine receptor Ligand 2,3-dihydro-1h-indol-5-ol Family 1 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Oestrogen receptor and Estrogen receptor beta Ligand 4-bromo-2... 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4'-am... 3 17
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-aminonaphthalen-1-ol... 2 34
Insulin receptor and Insulin-like growth factor 1 receptor Lig... 1 0
Fatty acid-binding protein Inhibitor 1-anilinonaphthalene-8-su... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Transient receptor potential cation channel subfamily V member... 3 15
Transient receptor potential cation channel subfamily V member... 9 21
Transient receptor potential cation channel subfamily V member... 6 1
Sigma non-opioid intracellular receptor 1 ligand CHEMBL154452 ... 2 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
Transient receptor potential cation channel subfamily V member... 2 0
Transient receptor potential cation channel subfamily V member... 1 0
Amyloid beta A4 protein inhibitor SureCN6372684 family 2 7
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(3-hydr... 1 0
Estradiol 17-beta-dehydrogenase 2 and Estradiol 17-beta-dehydr... 1 2
Benzene and Substituted Derivatives Metabolite 4-Hydroxy-2,6-d... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00281469 CHEMBL24462 Bioactive 189350-02-5
CFAMM00281455 DNC010103 Investigative Drug 4-(2-(diethylamino)ethylamino)-1-naphthol
CFAMM00281454 DNC010102 Investigative Drug 4-(Benzylamino)-1-naphthol
CFAMM00281453 DNC010101 Investigative Drug 4-(Cyclohexylamino)-1-naphthol
CFAMM00281466 DNC010095 Investigative Drug 4-(methylamino)naphthalen-1-ol
CFAMM00281452 DNC010100 Investigative Drug 4-(Pent-3-ylamino)-1-naphthol
CFAMM00281465 DNC010097 Investigative Drug 4-(propylamino)naphthalen-1-ol
CFAMM00281464 DNC010096 Investigative Drug 4-(ethylamino)naphthalen-1-ol
CFAMM00281463 DNC010099 Investigative Drug 4-(tert-butylamino)naphthalen-1-ol
CFAMM00281462 DNC010098 Investigative Drug 4-(Isopropylamino)-1-naphthol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543