CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2997
Family Name Neutrophil elastase Inhibitor 3-butyl-3-ethyl-1-phenylazetidine-2,4-dione Family
No. of Seeds 6 No. of Other Members 5
Family Centroid CFAMM00281571 Functional Category Investigative Drug
Superfamily Neutrophil elastase Inhibitor 3-butyl-3-ethyl-1-phenylazetidine-2,4-dione Superfamily
Class Class 2630

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Pan-DAC Inhibitor AR-42 Family 21 153
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Transient receptor potential cation channel subfamily V member... 6 33
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Fatty-acid amide hydrolase 1 Inhibitor 1-biphenyl-4-ylmaleimid... 2 11
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Tyrosinase Inhibitor S-2-(o-toluidino)-2-oxoethyl Carbamothioa... 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Neutrophil elastase inhibitor 3,3-diethyl-1-[4-(phenylsulfanyl... 1 0
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Substance-P receptor ligand AGN-PC-01XQZB family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00281564 DNC010137 Investigative Drug 3,3-Diethyl-1-o-tolylazetidine-2,4-dione
CFAMM00281573 DNC010143 Investigative Drug 3-Benzyl-3-methyl-1-phenylazetidine-2,4-dione
CFAMM00281572 DNC010142 Investigative Drug 3-Benzyl-3-ethyl-1-phenylazetidine-2,4-dione
CFAMM00281571 DNC010141 Investigative Drug 3-butyl-3-ethyl-1-phenylazetidine-2,4-dione
CFAMM00281570 DNC010140 Investigative Drug 3-Ethyl-3-isobutyl-1-phenylazetidine-2,4-dione
CFAMM00281565 DNC010136 Investigative Drug 3,3-diethyl-1-phenylazetidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543