CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3000
Family Name Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)-3-chlorobenzamide Family
No. of Seeds 4 No. of Other Members 20
Family Centroid CFAMM00281598 Functional Category Investigative Drug
Superfamily Retinoic acid receptor RXR-alpha and MO15-related protein kinase Pfmrk Binder Superfamily
Class Class 1913

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Transient receptor potential cation channel subfamily V member... 6 33
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Liver carboxylesterase 1 Inhibitor 4-chloro-1h-indole-2,3-dion... 3 7
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Transient receptor potential cation channel subfamily V member... 1 5
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Cruzipain Inhibitor N1,n4-bis(5-chloro-2-methylphenyl)succinam... 1 5
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 13 42
Substance-K receptor and Substance-P receptor ligand N-[4-[[4-... 1 4
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 2
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Transient receptor potential cation channel subfamily V member... 1 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Histamine H3 receptor ligand AGN-PC-0CW63F family 1 1
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
Muscarinic acetylcholine receptor M1 and Beta-lactamase ligand... 1 1
Chitin synthase 1 inhibitor AC1O53V7 family 9 0
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
C-C chemokine receptor type 2 ligand AGN-PC-00D2HV family 2 2
Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 i... 1 0
Proteinase-activated receptor 1 ligand 2-bromo-N-[3-(butanoyla... 4 0
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0
G protein-activated inward rectifier potassium channel 4 and G... 1 0
Lysophosphatidic acid receptor 3 and Microtubule-associated pr... 1 1
1-benzoyl-6-chloro-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00281621 DNC014240 Investigative Drug 3-chloro-N-(3-isobutyramidophenyl)benzamide
CFAMM00281608 DNC010145 Investigative Drug 3-chloro-N-(4-(phenyldiazenyl)phenyl)benzamide
CFAMM00281606 DNC014239 Investigative Drug 2-chloro-N-(3-(3-chlorobenzamido)phenyl)benzamide
CFAMM00281598 DNC014241 Investigative Drug N-(3-acetamidophenyl)-3-chlorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23731 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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