CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3024
Family Name Telomerase reverse transcriptase Inhibitor NSC-745794 Family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00282482 Functional Category Investigative Drug
Superfamily Vasopressin V1a receptor and Vasopressin V2 receptor Ligand Conivaptan Superfamily
Class Class 86

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Tubulin beta chain Inhibitor Mebendazole Family 12 84
BIBT986 family 7 96
CC-486 family 7 103
Vascular endothelial growth factor receptor 2 Ligand 6-(1h-ben... 2 5
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Adenosine receptor A2a ligand AGN-PC-01LVXW family 2 25
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00282480 DNC010234 Investigative Drug NSC-745799
CFAMM00282483 DNC010235 Investigative Drug NSC-745883
CFAMM00282482 DNC010231 Investigative Drug NSC-745794

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26853 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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