CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3032
Family Name Oxytocin receptor and Vasopressin V1a receptor Ligand PF-3274167 Family
No. of Seeds 4 No. of Other Members 36
Family Centroid CFAMM00282638 Functional Category Investigative Drug
Superfamily Oxytocin receptor and Vasopressin V1a receptor Ligand PF-3274167 Superfamily
Class Class 2640

Cousin Family NamesSeedsMembers
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 37
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 31 11
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Sodium/glucose cotransporter 2 inhibitor AGN-PC-0A9QFQ family 1 2
Sodium/glucose cotransporter 2 inhibitor AGN-PC-0A9T2L family 1 0
Sodium/glucose cotransporter 2 inhibitor AGN-PC-0A9UCA family 4 1
Sodium/glucose cotransporter 2 inhibitor AGN-PC-0A9TPG family 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 5 9
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Metabotropic glutamate receptor 5 ligand SureCN4297614 family 2 5
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 7 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Receptor tyrosine-protein kinase erbB-2 ligand N-[3-chloro-4-(... 4 3
Receptor tyrosine-protein kinase erbB-2 ligand 2-[2-[4-[3-chlo... 4 5
Hepatocyte growth factor receptor and Cytochrome P450 3A4 liga... 5 2
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 25 2
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 2
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 1-... 8 6
Metabotropic glutamate receptor 2 ligand 8-chloro-3-(cycloprop... 6 2
Acyl-CoA desaturase 1 inhibitor 3-[6-[4-(2-chlorophenoxy)piper... 2 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Motilin receptor ligand SureCN2012437 family 4 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 12 2
Adenosine receptor A2a ligand 8-(3-fluorophenyl)-3-[2-[4-[4-(2... 5 0
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 14 3
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 0
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 7 5
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Oxytocin receptor ligand AGN-PC-07C71T family 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor AGN-PC... 2 0
Acyl-CoA desaturase 1 inhibitor Pyridazine, 3-[4-(2-ethylpheno... 4 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-cyc... 1 0
Transitional endoplasmic reticulum ATPase inhibitor 3-[3-cyclo... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00282647 CHEMBL375515 Bioactive SureCN13953002
CFAMM00282646 CHEMBL376117 Bioactive 3-[4-(2-chlorophenoxy)piperidin-1-yl]-6-pyrrol-1-ylpyridazine
CFAMM00282663 CHEMBL565189 Bioactive 2-(2-chloro-3,6-difluorophenoxy)-5-[4-(6-methoxypyridin-3-yl)-5-methyl-1,2,4-triazol-3-yl]pyrazine
CFAMM00282638 DNC010247 Investigative Drug PF-3274167

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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