CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3039
Family Name Serine/threonine-protein kinase mTOR Inhibitor (4-(6-morpholino-9h-purin-2-yl)phenyl)methanol Family
No. of Seeds 2 No. of Other Members 11
Family Centroid CFAMM00282716 Functional Category Investigative Drug
Superfamily Cyclin-dependent kinase 2 Inhibitor Seliciclib Superfamily
Class Class 920

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 13
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Tyrosine kinase Inhibitor PKI166 Family 17 198
Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Peptide deformylase, mitochondrial Inhibitor 8-(2,3,4-trimetho... 8 15
Methylated-DNA--protein-cysteine methyltransferase Inhibitor 6... 4 5
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Proto-oncogene tyrosine-protein kinase Src and Cyclin-dependen... 2 1
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
Proto-oncogene tyrosine-protein kinase Src and Epidermal growt... 9 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 17
Acyl-CoA desaturase 1 and Acyl-CoA desaturase inhibitor 2-[4-[... 2 6
Serine/threonine-protein kinase Chk1 inhibitor SureCN6387344 f... 6 11
Vascular endothelial growth factor receptor 2 and Vascular end... 4 2
Vascular endothelial growth factor receptor 2 and Vascular end... 1 1
G2/mitotic-specific cyclin-B2 and Cyclin-dependent kinase 1 in... 2 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
propanoate NP Methyl 3-(4-((9h-purin-6-yl)amino)phenyl)propano... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00282715 DNC010265 Investigative Drug 3-(6-morpholino-9H-purin-2-yl)phenol
CFAMM00282716 DNC010262 Investigative Drug (4-(6-morpholino-9H-purin-2-yl)phenyl)methanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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