CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3047
Family Name Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tolyl-4h-chromene-4-thione Family
No. of Seeds 4 No. of Other Members 11
Family Centroid CFAMM00283067 Functional Category Investigative Drug
Superfamily Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tolyl-4h-chromene-4-thione Superfamily
Class Class 426

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Translocator protein Inhibitor Dextofisopam Family 3 250
Cathepsin S Inhibitor 2-[(2',3',4'-trifluorobiphenyl-2-yl)oxy]... 2 16
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Carbonic anhydrase 2 Inhibitor Sulfamic Acid Chroman-2-ylmethy... 1 5
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene ... 3 85
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Androgen receptor Ligand Palodesangren E Family 12 43
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Carbonic anhydrase 1 and Carbonic anhydrase 14 inhibitor (NZ)-... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (6aR,... 1 3
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor 6-[te... 1 0
Cannabinoid receptor 1 and Monoglyceride lipase ligand 4-(4-ph... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283066 DNC010298 Investigative Drug 7-methyl-2-p-tolyl-4H-chromene-4-thione
CFAMM00283063 DNC010300 Investigative Drug 7-fluoro-2-(4-fluorophenyl)-4H-chromene-4-thione
CFAMM00283062 DNC010302 Investigative Drug 2-p-tolyl-4H-chromene-4-thione
CFAMM00283067 DNC010299 Investigative Drug 7-fluoro-2-p-tolyl-4H-chromene-4-thione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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