CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3049
Family Name 5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine transporter Ligand 2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine Family
No. of Seeds 3 No. of Other Members 24
Family Centroid CFAMM00283181 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine transporter Binder Superfamily
Class Class 1004

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Neuronal acetylcholine receptor subunit beta-2 Ligand ABT-594 ... 4 5
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 1 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 11 4
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
Metabotropic glutamate receptor 5 ligand 2-chloro-6-[(2-methyl... 1 4
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 7
Potassium voltage-gated channel subfamily KQT member 2 ligand ... 3 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 8
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[7-(2-chloropheny... 2 0
Enoyl-acyl-carrier protein reductase inhibitor Triclosan deriv... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283182 DNC010336 Investigative Drug 1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine
CFAMM00283181 DNC010333 Investigative Drug 2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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