CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3052
Family Name Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B Inhibitor 8-benzyloxycaffeine Family
No. of Seeds 6 No. of Other Members 14
Family Centroid CFAMM00283283 Functional Category Investigative Drug with Natural Product
Superfamily Adenosine receptor A2a and Amine oxidase [flavin-containing] B Binder Superfamily
Class Class 1027

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
GP-531 family 1 33
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Survival motor neuron protein and Microtubule-associated prote... 2 14
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 2 0
Calpain-1 catalytic subunit and Calpain-2 catalytic subunit in... 4 0
Adenosine receptor A1 and Adenosine receptor A2a ligand benzyl... 1 0


External ID

Functional Category

Molecule Name

CFAMM00283287 DNC010358 Investigative Drug 8-(3-Fluorobenzyloxy)caffeine
CFAMM00283286 DNC010359 Investigative Drug 8-[(3-Trifluoromethyl)benzyloxy]caffeine
CFAMM00283285 DNC010356 Investigative Drug 8-(3-Chlorobenzyloxy)caffeine
CFAMM00283272 DNC010360 Investigative Drug 8-(3-Methylbenzyloxy)caffeine
CFAMM00283284 DNC010357 Investigative Drug 8-(3-Bromobenzyloxy)caffeine
CFAMM00283283 DNC010355 Investigative Drug 8-Benzyloxycaffeine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



59096 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543