Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database. Cousin Family Names Seeds Members Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911 Epidermal Growth Factor family 111 209 HIV protease Inhibitor Indinavir Family 36 211 Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256 Insulin receptor Ligand Insulin, Porcine Family 61 205 Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259 Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209 Renin Inhibitor Remikiren Family 100 126 Bacterial outer membrane Inhibitor Daptomycin Family 6 50 Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156 ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151 CBP-501 family 7 8 AEZS-108 family 5 2 Eluxadoline family 4 85 Cholecystokinin receptor type A Ligand A-71378 Family 77 23 Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142 Caspase-9 Inhibitor Z-lehd-fmk Family 1 0 5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24 Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41 Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2 Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54 Glycylpeptide N-tetradecanoyltransferase Inhibitor SC-58272 Fa... 2 11 Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0 Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67 Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17 Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60 Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2 Reverse transcriptase Inhibitor Atevirdine Family 4 55 Histamine H3 receptor Ligand Verongamine Family 1 0 Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72 Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15 Falcipain-2B Inhibitor FITC-LMNNAEHINQFYMFI Family 3 5 Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14 Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0 Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7 Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70 Pol polyprotein and Protease inhibitor 161186-52-3 family 3 3 Renin and Cathepsin D inhibitor tert-butyl N-[(2R)-1-[[3-[[(2R... 19 4 Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10 Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1 Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0 Pol polyprotein inhibitor AC1LA3L0 family 3 2 Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0 Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 1 7 Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3 Renin inhibitor propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imid... 4 0 Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 2 2 Pol polyprotein and Renin inhibitor U-75875 family 12 1 Prothrombin inhibitor AGN-PC-09QMX4 family 1 4 Placenta growth factor inhibitor CHEMBL1689479 family 4 1 Pol polyprotein inhibitor N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimi... 5 4 Pol polyprotein inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-... 7 3 Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2 Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9 Histamine H3 receptor ligand AGN-PC-075YXY family 1 4 Platelet-derived growth factor receptor alpha and Vascular end... 3 1 RAC-alpha serine/threonine-protein kinase inhibitor 5-[5-[(2S)... 3 1 C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-[[4-(2-... 5 0 C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1 Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0 Renin inhibitor tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-h... 1 0 KiSS-1 receptor ligand (2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-... 3 0 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1 Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3 Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0 Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 4 1 Melanocortin receptor 4 ligand CHEMBL2415084 family 3 0 Renin inhibitor (4S)-5-cyclohexyl-2,2-difluoro-4-[[(2S)-3-(1H-... 1 0 Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0 Pol polyprotein inhibitor Palinavir deriv. 13 family 1 0 Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0 Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0 Type-2 angiotensin II receptor and Type-1A angiotensin II rece... 2 24 Renin inhibitor (2S,4S,5S)-6-cyclohexyl-4-hydroxy-N-(3-imidazo... 1 0 Substance-P receptor ligand N-[(2R)-1-[acetyl-[(2-chlorophenyl... 2 2 Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0 Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3 Renin inhibitor [(2S)-1-[[(2R)-1-[[(2S,3S)-1-cyclohexyl-3-hydr... 1 0 Histamine H3 receptor ligand AGN-PC-075YVW family 1 2 Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0 Neuropeptide Y receptor type 2 ligand CHEMBL411765 family 1 0 KiSS-1 receptor ligand N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-... 1 0 Epidermal growth factor receptor ligand CHEMBL437469 family 1 0 Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2 Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(1,3-benzodi... 1 0 Growth hormone secretagogue receptor type 1 ligand CHEMBL52599... 1 0 Renin inhibitor SureCN7300793 family 2 5 E3 ubiquitin-protein ligase Mdm2 and Protein Mdm4 inhibitor CH... 2 1 Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7 Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16g... 1 0 Glucagon receptor ligand CHEMBL267876 family 1 0 Putative NP ZINC40310254 Family 74 1
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00186889 CHEMBL305162 Bioactive
(3S,4R)-N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-3,4-bis(2-methoxyethoxymethoxy)pyrrolidine-1-carboxamide CFAMM00186867 CHEMBL2371489 Bioactive
(2S)-5-(diaminomethylideneamino)-2-[[(10R,13S,16S,19S,25S,28S,34S,42S)-34,39,42-triamino-19-(carboxymethyl)-13,25-bis[3-(diaminomethylideneamino)propyl]-28-(1H-imidazol-5-ylmethyl)-16-[(4-methoxyphenyl)methyl]-12,15,18,21,24,27,30,33,41-nonaoxo-7,8-dithia-11,14,17,20,23,26,29,32,38,40-decazaspiro[5.36]dotetracont-38-ene-10-carbonyl]amino]pentanoic acid CFAMM00186881 CHEMBL577128 Bioactive
CHEMBL577128 CFAMM00186845 CHEMBL1790564 Bioactive
(2R,3R,4R,5S)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-phenoxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-yloctanamide CFAMM00186860 CHEMBL277248 Bioactive
tert-butyl N-[1-[[1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(4-methylpentanoylamino)pentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]carbamate CFAMM00186851 CHEMBL2372772 Bioactive
(2S)-2-[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-hydroxypropanoyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]oxypropanoic acid CFAMM00186816 CHEMBL407023 Bioactive
(2S)-N-[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-6-(propan-2-ylamino)hexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-6-[[butylamino-(cyanoamino)methylidene]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide CFAMM00186830 CHEMBL58859 Bioactive
(2S)-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-[[2-(2-methoxyethoxymethoxy)ethyl-methylcarbamoyl]amino]-3-(4-methoxyphenyl)propanamide CFAMM00186894 CHEMBL58968 Bioactive
N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-2-methylpropanamide CFAMM00186844 CHEMBL309345 Bioactive
N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]morpholine-4-carboxamide CFAMM00186823 CHEMBL3037789 Bioactive
CHEMBL3037789 CFAMM00186872 CHEMBL280503 Bioactive
N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]morpholine-4-carboxamide CFAMM00186887 CHEMBL293094 Bioactive
2-[3-[[[(2S)-2-[[3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]propanoyl]amino]-6-methylheptanoyl]amino]-4-methylpentanoyl]amino]methyl]phenoxy]acetic acid CFAMM00186879 CHEMBL3037790 Bioactive
CHEMBL3037790 CFAMM00186893 CHEMBL299892 Bioactive
2-[3-[[[(2S)-2-[[5-cyclohexyl-3-hydroxy-4-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]propanoyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]methyl]phenoxy]acetic acid CFAMM00186829 CHEMBL54886 Bioactive
tert-butyl N-[(2S)-1-[[(2S)-1-[[3-hydroxy-1-[[(2S)-1-[(4-methoxyphenyl)methylamino]-4-methyl-1-oxopentan-2-yl]amino]-6-methyl-1-oxoheptan-4-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate CFAMM00186871 CHEMBL334426 Bioactive
(2R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-phenoxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide CFAMM00186822 CHEMBL3037788 Bioactive
CHEMBL3037788 CFAMM00186886 CHEMBL234198 Bioactive
CHEMBL234198 CFAMM00186849 CHEMBL45727 Bioactive
tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-cyclohexyl-3-hydroxy-5-propan-2-ylsulfonylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]carbamate CFAMM00186864 CHEMBL556348 Bioactive
SureCN7299673 CFAMM00186814 CHEMBL59236 Bioactive
(2S)-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-[[2-(methoxymethoxy)ethyl-methylcarbamoyl]amino]-3-(4-methoxyphenyl)propanamide CFAMM00186828 CHEMBL58351 Bioactive
(2S)-N-[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-[[2,3-dihydroxypropyl(methyl)carbamoyl]amino]-3-(4-methoxyphenyl)propanamide CFAMM00186892 CHEMBL61777 Bioactive
N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]morpholine-4-carboxamide CFAMM00186856 CHEMBL412704 Bioactive
CHEMBL412704 CFAMM00186821 CHEMBL3037785 Bioactive
CHEMBL3037785 CFAMM00186877 CHEMBL281436 Bioactive
N-[(2S)-1-[[(2S)-1-[[(2R,3S,4R)-5-azido-1-cyclohexyl-3,4-dihydroxypentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-2-methylpropanamide CFAMM00186891 CHEMBL268351 Bioactive
CHEMBL268351 CFAMM00186841 CHEMBL69634 Bioactive
tert-butyl N-[1-[[1-[[(2S,3R)-1-cyclohexyl-3-hydroxy-4-propan-2-ylsulfonylbutan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]carbamate CFAMM00186869 CHEMBL2440187 Bioactive
CHEMBL2440187 CFAMM00186820 CHEMBL61428 Bioactive
(3R,4S)-N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cyclohexyl-1-[(5S)-3-ethyl-2-oxo-1,3-oxazolidin-5-yl]-1-hydroxypropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-3,4-dihydroxypyrrolidine-1-carboxamide CFAMM00186883 CHEMBL94539 Bioactive
4-amino-N-[(2S)-1-[[(2S)-1-[[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-pyridin-2-ylhexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]cyclohexane-1-carboxamide CFAMM00186833 CHEMBL571742 Bioactive
CHEMBL571742 CFAMM00186890 CHEMBL2372778 Bioactive
(2S)-2-[(2S)-1-[(2S)-2-[[(2S)-2-cyclohexyl-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[(2-hydroxyacetyl)amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]oxypropanoic acid CFAMM00186832 CHEMBL571743 Bioactive
CHEMBL571743 CFAMM00186846 CHEMBL1790560 Bioactive
(2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-phenoxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide CFAMM00186862 DNC000604 Investigative Drug
Enalkiren
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00186875 CHEMBL165706 Bioactive
(2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide CFAMM00186815 CHEMBL318803 Bioactive
160495-86-3 CFAMM00186878 CHEMBL1790545 Bioactive
U-75875 CFAMM00186834 CHEMBL477467 Bioactive
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-(4-methoxyphenyl)butan-2-one;dihydrochloride CFAMM00186876 CHEMBL64958 Bioactive
161186-51-2 CFAMM00186825 CHEMBL367066 Bioactive
N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-3-(phenylsulfanylmethoxy)pyridine-2-carboxamide CFAMM00186853 CHEMBL307682 Bioactive
(2S)-N-[(4S,5R,6R,7R)-5,6-dihydroxy-2-methyl-12-(methylamino)-8-oxo-7-propan-2-yldodecan-4-yl]-3-(1H-imidazol-5-yl)-2-[(2-phenoxyacetyl)amino]propanamide CFAMM00186895 CHEMBL568965 Bioactive
(2R)-2-[[(2R)-2-[[(2S)-2-[[(2E,4E)-5-(1,3-benzodioxol-5-yl)penta-2,4-dienoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide CFAMM00186824 CHEMBL568940 Bioactive
(2R)-2-[[(2R)-2-[[(2S)-2-[[(E)-3-(1,3-benzodioxol-5-yl)prop-2-enoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide CFAMM00186866 CHEMBL1790514 Bioactive
N-[(2S,3R,5R)-5-[[(2S,3S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-3-(phenoxymethoxy)pyridine-2-carboxamide CFAMM00186837 CHEMBL333707 Bioactive
tert-butyl N-[(2S)-1-[[(2S)-1-[(1-cyclohexyl-3-hydroxy-5-pyridin-2-yloxypentan-2-yl)amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate CFAMM00186865 CHEMBL1790512 Bioactive
N-[(2S,3R,4R,5R)-5-[[(2S,3S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-3-(phenylsulfanylmethoxy)pyridine-2-carboxamide CFAMM00186843 CHEMBL327068 Bioactive
tert-butyl N-[(2S)-1-[[(2S)-1-[(1-cyclohexyl-3-hydroxy-4-pyridin-2-yloxybutan-2-yl)amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate CFAMM00186848 CHEMBL2304142 Bioactive
(2S,5S)-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)octanamide CFAMM00186897 CHEMBL417209 Bioactive
(2S)-2-[[3-[[1H-imidazol-5-ylmethyl-[(4-methoxyphenyl)methyl]amino]methyl]benzoyl]amino]-4-methylsulfanylbutanoic acid CFAMM00186826 CHEMBL559158 Bioactive
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-(4-methoxyphenyl)butan-2-one;hydrochloride CFAMM00186854 CHEMBL1790557 Bioactive
(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)octanamide CFAMM00186868 CHEMBL421909 Bioactive
(2R)-3,4-dihydroxy-6-(1H-imidazol-5-yl)-N-[(2S)-2-methylbutyl]-5-[(2-phenoxyacetyl)amino]-2-propan-2-ylhexanamide CFAMM00186882 CHEMBL569222 Bioactive
(2R)-2-[[(2R)-2-[[(2S)-2-[5-(1,3-benzodioxol-5-yl)pentanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide CFAMM00186839 CHEMBL305100 Bioactive
2-Aminobenzyl-Substituted AHPPA deriv. 11 CFAMM00186818 CHEMBL165480 Bioactive
(2S,4S,5S)-6-cyclohexyl-4-hydroxy-5-[[(2S)-3-(1-methylimidazol-4-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide CFAMM00186831 CHEMBL552551 Bioactive
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-(4-phenoxyphenyl)butan-2-one;hydrochloride CFAMM00186858 CHEMBL556799 Bioactive
(3S)-3-amino-4-(1H-imidazol-5-yl)-1-[4-[(2,3,4,5,6-pentafluorophenyl)methoxy]phenyl]butan-2-one;hydrochloride CFAMM00186850 CHEMBL336336 Bioactive
(2R)-3,4-dihydroxy-6-(1H-imidazol-5-yl)-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-5-[(2-phenoxyacetyl)amino]-2-propan-2-ylhexanamide CFAMM00186900 CHEMBL130039 Bioactive
(5S)-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-yloctanamide CFAMM00186835 CHEMBL1790965 Bioactive
(2R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)hexanamide CFAMM00186870 CHEMBL1276270 Bioactive
tert-butyl N-[(3S,6S,9S)-9-[[[(2S)-1-(butylamino)-3-methyl-1-oxobutan-2-yl]amino]methyl]-6-(1H-imidazol-5-ylmethyl)-4,7-dioxo-14-oxa-5,8-diazabicyclo[13.4.0]nonadeca-1(19),15,17-trien-3-yl]carbamate CFAMM00186899 CHEMBL1790972 Bioactive
(2R,5S)-3,4-dihydroxy-5-[[3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-7-methyl-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-(2-methylpropyl)octanamide CFAMM00186827 CHEMBL176737 Bioactive
N-[(3R,4R,5R)-5-[[(2S)-1-(1H-benzimidazol-2-ylmethylamino)-3-methyl-1-oxopentan-2-yl]carbamoyl]-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]pyridine-2-carboxamide CFAMM00186855 CHEMBL1790558 Bioactive
(2R,3R,4R,5S)-6-cyclohexyl-2-(cyclohexylmethyl)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]hexanamide CFAMM00186847 CHEMBL2304144 Bioactive
(2R,5S)-6-cyclohexyl-2-(cyclohexylmethyl)-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3R)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]hexanamide CFAMM00186840 CHEMBL285955 Bioactive
(2S)-N-[(2S,3S)-1-cyclohexyl-3-hydroxy-5-(3-imidazol-1-ylpropylamino)-5-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[3-(3-oxopyrido[4,3-b][1,4]oxazin-4-yl)propanoylamino]-3-phenylpropanoyl]amino]pentanamide CFAMM00186819 CHEMBL104326 Bioactive
154030-79-2 CFAMM00186896 CHEMBL174307 Bioactive
AC1NUJK3 CFAMM00186861 CHEMBL48804 Bioactive
(2R,3R,4R,5S)-2-benzyl-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-6-phenylhexanamide CFAMM00186901 ZINC40313230 Natural Product
methyl 6-(4-(4-methoxyphenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxamido)hexanoate CFAMM00186857 ZINC40313227 Natural Product
methyl 6-[[(4R)-4-(4-methoxyphenyl)-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-5-carbonyl]amino]hexanoate CFAMM00186885 ZINC20759334 Natural Product
2-(4-ethoxyphenyl)-N-(2-oxo-2-spiro[1,5,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-4,4'-piperidine]-1'-ylethyl)acetamide CFAMM00186863 ZINC20759504 Natural Product
3-(4-methoxyphenyl)-N-[(2S)-4-methylsulfanyl-1-oxo-1-spiro[1,5,6,7-tetrahydroimidazo[4,5-c]pyridin-3-ium-4,4'-piperidine]-1'-ylbutan-2-yl]propanamide CFAMM00186874 57138251 Patent Compound
CFAMM00186888 12802340 Patent Compound
CFAMM00186838 53946844 Patent Compound
SureCN7649711 CFAMM00186880 57015659 Patent Compound
CFAMM00186842 53745155 Patent Compound
SureCN1171906
Statistics of CFAM Database
490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
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Dr.
Chen Yuzong Deputy
Director of Center for Computational Science and Engineering All rights reserved.
