CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3066
Family Name DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00283386 Functional Category Investigative Drug
Superfamily DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Superfamily
Class Class 1528

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
BIBT986 family 7 96
CC-486 family 7 103
Eluxadoline family 4 85
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-7-[1H-b... 3 6
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 3
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor ethyl 4-(4-carbamoyl-... 2 15
Thyroid hormone receptor beta ligand CHEMBL1325165 family 1 6
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Gastrin/cholecystokinin type B receptor ligand 3-[[5-[2-(1-ada... 9 15
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 2
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283389 CHEMBL2086736 Bioactive 3-[1,3-dihydrobenzimidazol-2-ylidene(phenyl)methyl]-2-oxoindole-5-carboxylic acid
CFAMM00283384 CHEMBL2086740 Bioactive 3-[1,3-dihydrobenzimidazol-2-ylidene-(4-methylphenyl)methyl]-2-oxoindole-5-carboxylic acid
CFAMM00283386 DNC010384 Investigative Drug NSC-57893

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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