CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3069
Family Name Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyloxy)phenylcarbamate Family
No. of Seeds 15 No. of Other Members 9
Family Centroid CFAMM00283443 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 and Histone deacetylase 1 Binder Superfamily
Class Class 1579

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Cyclooxygenase Inhibitor Acetaminophen Family 2 42
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Histamine H3 receptor Ligand UCL1972 Family 3 23
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Carbonic anhydrase 2 Inhibitor 4-methoxyphenylsulfamide Family 2 27
Histone deacetylase 1 Inhibitor 7-(4-(dimethylamino)phenoxy)-n... 2 1
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-(hexyl... 12 4
Fatty-acid amide hydrolase 1 Inhibitor Benzaldehyde O-4-ethoxy... 21 4
Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Bip... 3 7
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor SureCN... 2 11
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neutrophil elastase inhibitor AGN-PC-04S1IE family 1 0
Lysophosphatidic acid receptor 2 and Lysophosphatidic acid rec... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Hormone-sensitive lipase and Acetylcholinesterase inhibitor Su... 2 0
Protein-S-isoprenylcysteine O-methyltransferase inhibitor N-[2... 1 2
Transient receptor potential cation channel subfamily V member... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283436 DNC010440 Investigative Drug 2-fluorophenyl 4-(hexyloxy)phenylcarbamate
CFAMM00283429 DNC010432 Investigative Drug 2-fluorophenyl 4-phenoxyphenylcarbamate
CFAMM00283443 DNC010395 Investigative Drug 2-fluorophenyl 4-(octyloxy)phenylcarbamate
CFAMM00283435 DNC010441 Investigative Drug 2-fluorophenyl 4-(decyloxy)phenylcarbamate
CFAMM00283428 DNC010439 Investigative Drug phenyl 4-(dodecyloxy)phenylcarbamate
CFAMM00283427 DNC010438 Investigative Drug phenyl 4-(undecyloxy)phenylcarbamate
CFAMM00283433 DNC010437 Investigative Drug phenyl 4-(decyloxy)phenylcarbamate
CFAMM00283449 DNC010398 Investigative Drug 2-fluorophenyl 4-(dodecyloxy)phenylcarbamate
CFAMM00283432 DNC010436 Investigative Drug phenyl 4-(octyloxy)phenylcarbamate
CFAMM00283446 DNC010393 Investigative Drug 2-fluorophenyl 4-butoxyphenylcarbamate
CFAMM00283431 DNC010435 Investigative Drug phenyl 4-(heptyloxy)phenylcarbamate
CFAMM00283445 DNC010397 Investigative Drug 2-fluorophenyl 4-(undecyloxy)phenylcarbamate
CFAMM00283437 DNC010442 Investigative Drug 4-fluorophenyl 4-butoxyphenylcarbamate
CFAMM00283430 DNC010434 Investigative Drug phenyl 4-(hexyloxy)phenylcarbamate
CFAMM00283444 DNC010394 Investigative Drug 2-fluorophenyl 4-(heptyloxy)phenylcarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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