CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3070
Family Name Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phenyl 4-butoxybenzylcarbamate Family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00283455 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 Binder Superfamily 6
Class Class 184

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Acetylcholinesterase Inhibitor Rivastigmine Family 2 59
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Zucapsacin family 7 177
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Substance-P receptor Ligand Ezlopitant Family 10 207
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Dapoxetine family 3 40
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Arachidonate 5-lipoxygenase Inhibitor Bw A4C Family 3 18
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 11
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)met... 17 24
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-butoxy... 1 1
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Amine oxidase [flavin-containing] B Inhibitor (r)-n2-{4-[(3-ch... 3 0
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Fatty-acid amide hydrolase 1 Inhibitor 3-(4,5-dihydrooxazol-2-... 6 11
Cathepsin K inhibitor [1-(3-methoxyphenyl)-2-methylpropan-2-yl... 2 10
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 8 4
Cholinesterase and Acetylcholinesterase inhibitor AGN-PC-009M2... 1 6
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 0
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Chymase inhibitor 1,3-bis[(3-methoxyphenyl)methyl]-1,3-diazeti... 3 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-006SR... 1 2
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
N-acylethanolamine-hydrolyzing acid amidase inhibitor (4-pheny... 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-074BAX family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283454 DNC010403 Investigative Drug 3-chlorophenyl 4-butoxybenzylcarbamate
CFAMM00283453 DNC010400 Investigative Drug 4-methoxyphenyl 1-(4-butoxyphenyl)propylcarbamate
CFAMM00283455 DNC010402 Investigative Drug 3-(trifluoromethyl)phenyl 4-butoxybenzylcarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27430 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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