CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3072
Family Name Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-(hexyloxy)phenylcarbamoyl Oxime Family
No. of Seeds 12 No. of Other Members 4
Family Centroid CFAMM00283484 Functional Category Investigative Drug
Superfamily Fatty-acid amide hydrolase 1 and Histone deacetylase 1 Binder Superfamily
Class Class 1579

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
D(2) dopamine receptor Ligand Pardoprunox Family 4 81
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Histone deacetylase 1 Inhibitor 7-(4-(dimethylamino)phenoxy)-n... 2 1
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
Fatty-acid amide hydrolase 1 Inhibitor Benzaldehyde O-4-ethoxy... 21 4
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 9
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor SureCN... 2 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-(2,... 2 11
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 1
Hormone-sensitive lipase and Acetylcholinesterase inhibitor Su... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283497 CHEMBL597216 Bioactive AGN-PC-031BY6
CFAMM00283491 CHEMBL599357 Bioactive AGN-PC-031BXY
CFAMM00283481 DNC010408 Investigative Drug propan-2-one O-4-ethoxyphenylcarbamoyl oxime
CFAMM00283487 DNC010411 Investigative Drug propan-2-one O-4-(pentyloxy)phenylcarbamoyl oxime
CFAMM00283480 DNC010409 Investigative Drug propan-2-one O-4-propoxyphenylcarbamoyl oxime
CFAMM00283486 DNC010410 Investigative Drug propan-2-one O-4-butoxyphenylcarbamoyl oxime
CFAMM00283485 DNC010413 Investigative Drug propan-2-one O-4-(heptyloxy)phenylcarbamoyl oxime
CFAMM00283484 DNC010412 Investigative Drug propan-2-one O-4-(hexyloxy)phenylcarbamoyl oxime
CFAMM00283490 DNC010415 Investigative Drug propan-2-one O-4-(nonyloxy)phenylcarbamoyl oxime
CFAMM00283483 DNC010430 Investigative Drug propan-2-one O-3-butoxyphenylcarbamoyl oxime
CFAMM00283489 DNC010414 Investigative Drug propan-2-one O-4-(octyloxy)phenylcarbamoyl oxime
CFAMM00283488 DNC010416 Investigative Drug propan-2-one O-4-(decyloxy)phenylcarbamoyl oxime

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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