CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3073
Family Name Fatty-acid amide hydrolase 1 Inhibitor Benzaldehyde O-4-ethoxyphenylcarbamoyl Oxime Family
No. of Seeds 21 No. of Other Members 4
Family Centroid CFAMM00283524 Functional Category Investigative Drug
Superfamily Tyrosinase and Fatty-acid amide hydrolase 1 Binder Superfamily
Class Class 2658

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
Fatty-acid amide hydrolase 1 Inhibitor Propan-2-one O-4-(hexyl... 12 4
Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Bip... 3 7
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Fatty-acid amide hydrolase 1 Inhibitor Phenmedipham Family 2 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Coagulation factor X and Cationic trypsin inhibitor 3-[(E)-3-[... 3 2
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 20 23
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Hormone-sensitive lipase and Acetylcholinesterase inhibitor Su... 2 0


External ID

Functional Category

Molecule Name

CFAMM00283509 CHEMBL596658 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-decoxyphenyl)carbamate
CFAMM00283527 CHEMBL598047 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-pentoxyphenyl)carbamate
CFAMM00283510 CHEMBL596659 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-undecoxyphenyl)carbamate
CFAMM00283526 CHEMBL596617 Bioactive [(E)-benzylideneamino] N-(4-dodecoxyphenyl)carbamate
CFAMM00283531 CHEMBL610214 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-hexoxyphenyl)carbamate
CFAMM00283517 CHEMBL597648 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-nonoxyphenyl)carbamate
CFAMM00283530 CHEMBL608147 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-dodecoxyphenyl)carbamate
CFAMM00283529 CHEMBL598048 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-heptoxyphenyl)carbamate
CFAMM00283515 CHEMBL597647 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-octoxyphenyl)carbamate
CFAMM00283528 CHEMBL598046 Bioactive [(E)-(4-fluorophenyl)methylideneamino] N-(4-butoxyphenyl)carbamate
CFAMM00283512 CHEMBL586217 Bioactive [(E)-benzylideneamino] N-(4-undecoxyphenyl)carbamate
CFAMM00283524 DNC010418 Investigative Drug benzaldehyde O-4-ethoxyphenylcarbamoyl oxime
CFAMM00283500 DNC010425 Investigative Drug benzaldehyde O-4-(nonyloxy)phenylcarbamoyl oxime
CFAMM00283499 DNC010426 Investigative Drug benzaldehyde O-4-(decyloxy)phenylcarbamoyl oxime
CFAMM00283505 DNC010420 Investigative Drug benzaldehyde O-4-butoxyphenylcarbamoyl oxime
CFAMM00283522 DNC010417 Investigative Drug benzaldehyde O-4-methoxyphenylcarbamoyl oxime
CFAMM00283504 DNC010421 Investigative Drug benzaldehyde O-4-(pentyloxy)phenylcarbamoyl oxime
CFAMM00283503 DNC010422 Investigative Drug benzaldehyde O-4-(hexyloxy)phenylcarbamoyl oxime
CFAMM00283502 DNC010423 Investigative Drug benzaldehyde O-4-(heptyloxy)phenylcarbamoyl oxime
CFAMM00283525 DNC010419 Investigative Drug benzaldehyde O-4-propoxyphenylcarbamoyl oxime
CFAMM00283501 DNC010424 Investigative Drug benzaldehyde O-4-(octyloxy)phenylcarbamoyl oxime

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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