CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3087
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor 2-(n-pyrrolidinyl)-3'-nitropropiophenone Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00283669 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Binder Superfamily
Class Class 2295

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Liver carboxylesterase 1 Inhibitor 1-(4-nitro-phenyl)-2-phenyl... 2 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 13
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Acetylcholinesterase inhibitor 2-[2-(1-benzylpiperidin-4-yl)et... 2 9
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Peptide deformylase inhibitor (2R)-2-[[formyl(hydroxy)amino]me... 2 1
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 2 1
Histamine H3 receptor ligand SureCN3058680 family 4 0
Transient receptor potential cation channel subfamily A member... 1 1
Mu-type opioid receptor ligand CHEMBL2310836 family 4 4
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 11
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrobenz... 1 1
Kappa-type opioid receptor ligand N-[(2S)-1-(2,5-dihydropyrrol... 1 1
Histone deacetylase 1 inhibitor AGN-PC-07ZGOT family 2 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor AGN-P... 2 0
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2
Aromatase inhibitor AGN-PC-00Q2PJ family 4 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
(8-methyl-6-oxo-1,2,3a,4,5,6-hexahydro-3H-3,10b-diazaacephenan... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283668 CHEMBL75723 Bioactive (4-nitrophenyl)-[1-(2-phenylethyl)piperidin-4-yl]methanone
CFAMM00283669 DNC010481 Investigative Drug 2-(N-Pyrrolidinyl)-3'-nitropropiophenone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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