CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3090
Family Name Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl)-1h-imidazole Family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00283697 Functional Category Investigative Drug
Superfamily Cytochrome P450 11B1, mitochondrial and Steroid 17-alpha-hydroxylase/17,20 lyase Binder Superfamily
Class Class 1989

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Aromatase and Thromboxane-A synthase Inhibitor 6-(1h-imidazol-... 3 8
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 3 2
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 2 1
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(4-nitrob... 3 5
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 2 8
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(3,4-dich... 1 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 4
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-(2-(4-... 25 10
Histamine H1 receptor and Alpha-1B adrenergic receptor ligand ... 1 6
Delta-type opioid receptor and Kappa-type opioid receptor liga... 10 4
Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(2,4-difluor... 5 0
Heme oxygenase 1 and Heme oxygenase 2 inhibitor 1-imidazol-1-y... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283696 CHEMBL436369 Bioactive AGN-PC-075MOY
CFAMM00283698 DNC010497 Investigative Drug 1-(3-Bromobenzyl)-1H-imidazole
CFAMM00283697 DNC010492 Investigative Drug 1-(4-bromobenzyl)-1H-imidazole
CFAMM00283701 DNC013121 Investigative Drug N-3-(4-bromophenyl)propyl imidazole
CFAMM00283693 DNC013098 Investigative Drug 1-(3,5-dibromobenzyl)-1H-imidazole
CFAMM00283700 DNC013123 Investigative Drug 1-(4-bromophenethyl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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