CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3092
Family Name Cytochrome P450 11B1, mitochondrial Inhibitor Methyl 3-(1-benzyl-1h-imidazol-5-yl)-propanoate Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00283726 Functional Category Investigative Drug
Superfamily Cytochrome P450 11B1, mitochondrial Binder Superfamily
Class Class 1989

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Etomid... 3 10
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Histamine H3 receptor Ligand Proxyfan Family 12 32
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 3-(1-benzyl-1h-i... 3 5
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 1 0
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
Histamine H3 receptor and Histamine H2 receptor ligand SureCN7... 3 20
Histamine H3 receptor and Histamine H2 receptor ligand SureCN7... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3
Angiotensin-converting enzyme 2 inhibitor MLN-4760 family 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 1
Putative NP ZINC40309668 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00283714 CHEMBL592614 Bioactive SureCN3822953
CFAMM00283726 DNC010500 Investigative Drug Methyl 3-(1-Benzyl-1H-imidazol-5-yl)-propanoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43659 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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