CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3115
Family Name Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Ligand L-796568 Family
No. of Seeds 26 No. of Other Members 47
Family Centroid CFAMM00284282 Functional Category Investigative Drug
Superfamily Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Ligand L-796568 Superfamily
Class Class 2668

Cousin Family NamesSeedsMembers
Beta-3 adrenergic receptor Ligand Mirabegron Family 4 9
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 19 53
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 16 2
Beta-3 adrenergic receptor ligand 4,5-dichloro-N-[3-[(1R)-1-hy... 4 3
Beta-3 adrenergic receptor ligand 2-amino-N-[3-[(1R)-1-hydroxy... 7 0
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 6 0
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 1 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 1
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 4
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 1
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00284249 CHEMBL1684583 Bioactive SureCN1201015
CFAMM00284288 CHEMBL294753 Bioactive 4-[4-(4-tert-butylphenyl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284242 CHEMBL58798 Bioactive 4-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284255 CHEMBL195409 Bioactive 4-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl]-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284294 CHEMBL125963 Bioactive 4-[4-(2,3-difluorophenyl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284261 CHEMBL58407 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-naphthalen-2-yl-1,3-thiazol-2-yl)benzenesulfonamide
CFAMM00284241 CHEMBL291306 Bioactive 4-[4-(1-benzothiophen-2-yl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284267 CHEMBL193410 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-[(4-quinolin-6-yl-1,3-thiazol-2-yl)methyl]benzenesulfonamide
CFAMM00284260 CHEMBL331744 Bioactive SureCN8085385
CFAMM00284286 CHEMBL293994 Bioactive 4-[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284299 CHEMBL338794 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]benzenesulfonamide
CFAMM00284266 CHEMBL291593 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[(4-octyl-1,3-thiazol-2-yl)methyl]benzenesulfonamide
CFAMM00284279 CHEMBL430594 Bioactive 4-[4-[(4-fluorophenyl)methyl]-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284305 CHEMBL60281 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-octyl-1,3-thiazol-2-yl)benzenesulfonamide
CFAMM00284252 CHEMBL418308 Bioactive SureCN8085550
CFAMM00284304 CHEMBL338216 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[4-(3,4,5-trifluorophenyl)-1,3-thiazol-2-yl]benzenesulfonamide
CFAMM00284245 CHEMBL1684584 Bioactive SureCN1199582
CFAMM00284271 CHEMBL371427 Bioactive 4-[[4-(4-hexylphenyl)-1,3-thiazol-2-yl]methyl]-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284238 CHEMBL58241 Bioactive 4-[4-(4-hexylphenyl)-1,3-thiazol-2-yl]-N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284297 CHEMBL371220 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-4-[(4-quinolin-3-yl-1,3-thiazol-2-yl)methyl]benzenesulfonamide
CFAMM00284264 CHEMBL292598 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-quinolin-6-yl-1,3-thiazol-2-yl)benzenesulfonamide
CFAMM00284283 CHEMBL196081 Bioactive 4-[[4-(3,4-difluorophenyl)-1,3-thiazol-2-yl]methyl]-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]benzenesulfonamide
CFAMM00284250 CHEMBL291516 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]benzenesulfonamide
CFAMM00284296 CHEMBL111201 Bioactive L-796568
CFAMM00284237 CHEMBL293577 Bioactive N-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-4-(4-quinolin-3-yl-1,3-thiazol-2-yl)benzenesulfonamide
CFAMM00284282 DNC010594 Investigative Drug L-796568

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543