CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3126
Family Name Coagulation factor X and Potassium voltage-gated channel subfamily H member 2 Ligand RWJ-671818 Family
No. of Seeds 5 No. of Other Members 15
Family Centroid CFAMM00284801 Functional Category Investigative Drug
Superfamily Coagulation factor X and Potassium voltage-gated channel subfamily H member 2 Ligand RWJ-671818 Superfamily
Class Class 2145

Cousin Family NamesSeedsMembers
Prothrombin and Trypsin-1 inhibitor AGN-PC-073KRV family 3 4
Prothrombin and Trypsin-1 inhibitor AGN-PC-0750AE family 3 4
Prothrombin and Trypsin-1 inhibitor SureCN7255204 family 3 38
Prothrombin inhibitor N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tet... 2 1
Chymase and Chymotrypsin-C inhibitor 4-[[2-[5-amino-2-(3-methy... 4 14
Prothrombin and Coagulation factor VII inhibitor Pyrazinone An... 1 2
5-hydroxytryptamine receptor 2C ligand 3-methyl-6-[(2R)-2-meth... 2 0
5-hydroxytryptamine receptor 2C ligand 2-[2-(2-chlorophenyl)et... 4 0


External ID

Functional Category

Molecule Name

CFAMM00284803 CHEMBL1084908 Bioactive AGN-PC-07AJW2
CFAMM00284787 CHEMBL1087038 Bioactive N-[2-(diaminomethylideneamino)oxyethyl]-2-[3-(2,2-diphenylethylamino)-6-methyl-2-oxopyrazin-1-yl]acetamide
CFAMM00284807 CHEMBL1088332 Bioactive AGN-PC-07AK1B
CFAMM00284804 CHEMBL200960 Bioactive AGN-PC-075YUC
CFAMM00284801 DNC010635 Investigative Drug RWJ-671818

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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