CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3130
Family Name Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(1h-imidazol-4-yl)propyl Sec-butylcarbamate Family
No. of Seeds 26 No. of Other Members 80
Family Centroid CFAMM00285092 Functional Category Investigative Drug with Human Metabolite
Superfamily Histamine H3 receptor and Histamine H4 receptor Ligand (r)-3-(1h-imidazol-4-yl)propyl Sec-butylcarbamate Superfamily
Class Class 2675

Cousin Family NamesSeedsMembers
Histamine receptor Ligand Histamine Phosphate Family 6 78
Muscarinic acetylcholine receptor Ligand Pilocarpine Family 3 29
Polaprezinc family 2 19
Histamine H3 receptor Ligand Cipralisant Family 36 70
Cadherin-2 Inhibitor Exherin Family 2 9
Histamine H3 receptor and Histamine H4 receptor Ligand Thioper... 8 12
Histamine H3 receptor Ligand GT-2016 Family 4 6
Histamine H2 receptor and Histamine H3 receptor ligand N,N'-bi... 2 1
Histamine H3 receptor ligand SureCN7961197 family 1 0
Histamine H3 receptor and Histamine H4 receptor ligand IMIFURA... 3 4
Histamine H2 receptor and Histamine H1 receptor ligand N-[N'-[... 1 2


External ID

Functional Category

Molecule Name

CFAMM00285098 CHEMBL340932 Bioactive 3-(1H-imidazol-5-yl)propyl N-(dicyclopropylmethyl)carbamate
CFAMM00285085 CHEMBL130850 Bioactive 3-(1H-imidazol-5-yl)propyl N-(2,4-dimethylpentan-3-yl)carbamate
CFAMM00285073 CHEMBL2145442 Bioactive (Z)-but-2-enedioic acid;5-[3-(4-methylpentoxy)propyl]-1H-imidazole
CFAMM00285012 CHEMBL1076267 Bioactive 3-(1H-imidazol-5-yl)propyl N-[(2S)-2-methylbutyl]carbamate
CFAMM00285021 CHEMBL1788247 Bioactive 3-(1H-imidazol-5-yl)propyl N-[(1R)-1-cyclohexylethyl]carbamate
CFAMM00285104 CHEMBL345828 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-(3-methylpentyl)carbamate
CFAMM00285090 CHEMBL1081541 Bioactive 3-(1H-imidazol-5-yl)propyl N-(2-methylpentyl)carbamate
CFAMM00285046 CHEMBL1079552 Bioactive 3-(1H-imidazol-5-yl)propyl N-hexan-2-ylcarbamate
CFAMM00285083 CHEMBL154478 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-heptylcarbamate
CFAMM00285103 CHEMBL16056 Bioactive Carbamic acid, (cyclohexylmethyl)-, 3-(1H-imidazol-4-yl)propyl ester
CFAMM00285026 CHEMBL154840 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-(3-methylbutyl)carbamate
CFAMM00285082 CHEMBL2092970 Bioactive 3-(1H-imidazol-5-yl)propyl N-[(2S)-3,3-dimethylbutan-2-yl]carbamate
CFAMM00285109 CHEMBL329275 Bioactive tert-butyl N-[N-cyclohexyl-N'-[4-(1H-imidazol-5-yl)butyl]carbamimidoyl]carbamate
CFAMM00285088 CHEMBL155830 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-hexan-2-ylcarbamate
CFAMM00285065 CHEMBL156413 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-hexylcarbamate
CFAMM00285044 CHEMBL346573 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-octylcarbamate
CFAMM00285101 CHEMBL1081718 Bioactive 3-(1H-imidazol-5-yl)propyl N-(3-methylpentyl)carbamate
CFAMM00285093 CHEMBL128635 Bioactive 3-(1H-imidazol-5-yl)propyl N-[1-(1-methylcyclopropyl)ethyl]carbamate
CFAMM00285070 CHEMBL2145444 Bioactive (Z)-but-2-enedioic acid;5-[3-(3-methylbutoxy)propyl]-1H-imidazole
CFAMM00285035 CHEMBL154977 Bioactive (E)-but-2-enedioic acid;3-(1H-imidazol-5-yl)propyl N-pentylcarbamate
CFAMM00285074 CHEMBL2145443 Bioactive (Z)-but-2-enedioic acid;5-[3-(3,3-dimethylbutoxy)propyl]-1H-imidazole
CFAMM00285049 CHEMBL1788227 Bioactive 3-(1H-imidazol-5-yl)propyl N-[(2R)-3,3-dimethylbutan-2-yl]carbamate
CFAMM00285091 DNC010646 Investigative Drug (S)-3-(1H-imidazol-4-yl)propyl sec-butylcarbamate
CFAMM00285092 DNC010645 Investigative Drug (R)-3-(1H-imidazol-4-yl)propyl sec-butylcarbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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