CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3140
Family Name Tyrosine-protein phosphatase non-receptor type 1 and Neuraminidase Ligand Erysubin E Family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00285219 Functional Category Investigative Drug with Human Metabolite
Superfamily Neuraminidase and Androgen receptor Binder Superfamily
Class Class 605

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
Tyrosinase Inhibitor Monobenzone Family 6 197
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Salicin family 5 629
Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Glucokinase Inhibitor R7201 Family 22 105
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Acolbifene family 10 115
TS-071 family 8 36
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tubulin beta chain Inhibitor Combretastatin Family 3 5
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
Protein kinase C alpha type Inhibitor Acetoside Family 5 39
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 2 1
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Cytochrome P450 3A4 Inhibitor Hinokinin Family 2 10
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Beta-secretase 1 Inhibitor Eckol Family 6 40
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Tyrosinase Inhibitor Kazinol S Family 1 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 7
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4... 6 42
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
Estrogen receptor beta and Estrogen receptor ligand SureCN4017... 3 5
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Low affinity sodium-glucose cotransporter and Sodium/glucose c... 1 0
Platelet-activating factor receptor ligand (2S,3R,3aS)-2-(3,4-... 2 7
Arachidonate 5-lipoxygenase inhibitor SureCN9727677 family 1 2
Arachidonate 5-lipoxygenase inhibitor AGN-PC-073G1D family 1 0
Cytochrome P450 3A4 inhibitor 4-[(2E)-6-[(E)-3-hydroxy-2,6-dim... 3 2
Sodium/glucose cotransporter 2 inhibitor (2S,3R,4R,5S,6R)-2-[3... 1 4
Lignans and Norlignans Metabolite cis-Miyabenol C Family 3 0
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0
Coumarin NP Clausarin Family 1 0
3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole NP (3ar,5r,6s,6ar)... 18 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00285222 CHEMBL2048493 Bioactive (1R,2R,3S,4R,5R)-1-[2-ethoxy-5-[(4-ethylphenyl)methyl]phenyl]-5-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
CFAMM00285207 DNC014346 Investigative Drug ERYSTAGALLIN A
CFAMM00285219 DNC010671 Investigative Drug Erysubin E
CFAMM00285217 DNC010670 Investigative Drug Erybreadin D
CFAMM00285226 DNC014356 Investigative Drug Erythribyssin M
CFAMM00285211 DNC010665 Investigative Drug ERYTHRIBYSSIN A
CFAMM00285225 DNC014354 Investigative Drug erysubin D
CFAMM00285209 DNC014343 Investigative Drug Erythribyssin L
CFAMM00285224 DNC014355 Investigative Drug Erythribyssin D
CFAMM00285208 DNC014344 Investigative Drug cristacarpin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26848 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543