CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3146
Family Name Potassium voltage-gated channel subfamily A member 5 Ligand 2-amino-2-phenyl-1,1-di(pyridin-3-yl)ethanol Family
No. of Seeds 5 No. of Other Members 69
Family Centroid CFAMM00285449 Functional Category Investigative Drug with Natural Product
Superfamily Cytochrome P450 11B1, mitochondrial and Potassium voltage-gated channel subfamily A member 5 Binder Superfamily
Class Class 387

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Doxylamine Family 2 91
Citric Acid family 2 58
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 5 23
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapol Family 3 41
Melanocortin receptor 4 and Potassium voltage-gated channel su... 2 12
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
Glucocorticoid receptor ligand 1,1,1-trifluoro-2-[(1-methyl-3,... 3 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 5 8
Platelet-activating factor receptor ligand SureCN9852997 family 1 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 5
Nociceptin receptor and Potassium voltage-gated channel subfam... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1,1,1... 12 3
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10
Melanin-concentrating hormone receptor 1 and Potassium voltage... 7 1
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 2
Glutamate receptor ionotropic, NMDA 2B ligand SureCN8345160 fa... 1 2
Platelet-activating factor receptor ligand SureCN9575051 family 1 0
Histamine H3 receptor ligand AGN-PC-09M6FC family 1 9
Nuclear receptor ROR-gamma and Induced myeloid leukemia cell d... 1 1
Aromatase inhibitor AGN-PC-02KFLL family 1 0
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 0
Acetylcholine-binding protein and Neuronal acetylcholine recep... 1 5
Aromatase inhibitor AGN-PC-075MRV family 1 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 1 0
Pyridines and Derivatives Metabolite 4-Hydroxy-4-(3-pyridyl)-b... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00285389 CHEMBL200319 Bioactive AGN-PC-075YWS
CFAMM00285447 CHEMBL200171 Bioactive (1S)-3-[(3R)-3-methoxy-1-azabicyclo[2.2.2]octan-3-yl]-1-phenyl-1-pyridin-3-ylprop-2-yn-1-ol
CFAMM00285412 DNC010698 Investigative Drug 2-morpholino-2-phenyl-1,1-di(pyridin-3-yl)ethanol
CFAMM00285449 DNC010702 Investigative Drug 2-amino-2-phenyl-1,1-di(pyridin-3-yl)ethanol
CFAMM00285451 DNC010701 Investigative Drug 2-phenyl-1,1-di(pyridin-3-yl)ethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27036 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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