CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3153
Family Name Mitogen-activated protein kinase 14 Inhibitor Pamapimod Family
No. of Seeds 15 No. of Other Members 7
Family Centroid CFAMM00285595 Functional Category Investigative Drug
Superfamily Mitogen-activated protein kinase 14 Inhibitor Pamapimod Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
AP26113 family 16 90
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 10
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Hepatocyte growth factor receptor Ligand BMS-777607 Family 10 1
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Inositol monophosphatase 1 inhibitor CHEMBL1588383 family 1 6
Glycogen synthase kinase-3 beta inhibitor 6-[(2S)-2-(2-methoxy... 1 0
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Epidermal growth factor receptor ligand N-[3-[7-[2-methoxy-4-(... 9 3


External ID

Functional Category

Molecule Name

CFAMM00285590 CHEMBL1766505 Bioactive 6-(2,4-difluorophenoxy)-8-[(2S)-2,3-dihydroxypropyl]-2-(oxan-4-ylamino)pyrido[2,3-d]pyrimidin-7-one
CFAMM00285598 CHEMBL1766572 Bioactive AGN-PC-09M1L0
CFAMM00285601 CHEMBL1766499 Bioactive AGN-PC-02WJZD
CFAMM00285583 CHEMBL1232769 Bioactive 6-(2,4-difluorophenoxy)-8-methyl-2-[[(2R)-1-methylsulfonylpropan-2-yl]amino]pyrido[2,3-d]pyrimidin-7-one
CFAMM00285589 CHEMBL1766506 Bioactive AGN-PC-09M1KZ
CFAMM00285597 CHEMBL1766579 Bioactive AGN-PC-09M14X
CFAMM00285582 CHEMBL1232784 Bioactive 6-(2,4-difluorophenoxy)-8-methyl-2-[[(2S)-1-(tetrazol-2-yl)propan-2-yl]amino]pyrido[2,3-d]pyrimidin-7-one
CFAMM00285588 CHEMBL1766500 Bioactive AGN-PC-005GES
CFAMM00285586 CHEMBL1766502 Bioactive AGN-PC-09M1I7
CFAMM00285594 CHEMBL1232772 Bioactive SureCN13239789
CFAMM00285585 CHEMBL1766503 Bioactive AGN-PC-09M1KW
CFAMM00285593 CHEMBL1766580 Bioactive AGN-PC-02WJZS
CFAMM00285602 CHEMBL1766498 Bioactive SureCN5110069
CFAMM00285595 DNC010725 Investigative Drug PAMAPIMOD

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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