CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3158
Family Name Cyclin-dependent kinase 2 and G1/S-specific cyclin-E1 Inhibitor (2'z,3'e)-5-fluoro-5'-hydroxy-indirubin-3'-oxime Family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00285617 Functional Category Investigative Drug
Superfamily Cyclin-dependent kinase 2 and G1/S-specific cyclin-E1 Inhibitor (2'z,3'e)-5-fluoro-5'-hydroxy-indirubin-3'-oxime Superfamily
Class Class 2375

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Indeglitazar family 3 39
Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
5-hydroxytryptamine receptor 2A and Alpha-2A adrenergic recept... 4 29
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 0
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Substance-P receptor ligand 1-[4-(2-methoxyphenyl)piperazin-1-... 11 12
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Glycogen synthase kinase-3 beta and G2/mitotic-specific cyclin... 4 13
Glycogen synthase kinase-3 beta and G2/mitotic-specific cyclin... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00285618 DNC010736 Investigative Drug (2'Z,3'E)-5-Chloro-5'-hydroxy-indirubin-3'-oxime
CFAMM00285617 DNC010737 Investigative Drug (2'Z,3'E)-5-Fluoro-5'-hydroxy-indirubin-3'-oxime
CFAMM00285616 DNC010745 Investigative Drug (2'Z,3'E)-5-Nitro-5'-methoxy-indirubin-3'-oxime
CFAMM00285615 DNC010746 Investigative Drug (2'Z,3'E)-5-Fluoro-5'-methoxy-indirubin-3'-oxime
CFAMM00285619 DNC010735 Investigative Drug (2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23964 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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