CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3160
Family Name Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor NSC-645812 Family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00285623 Functional Category Investigative Drug with Natural Product
Superfamily Ribosyldihydronicotinamide dehydrogenase [quinone] and NAD(P)H dehydrogenase [quinone] 1 Binder Superfamily
Class Class 2375

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 8
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-645827 Family 1 4
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 3 13
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 4
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Adenosine receptor A3 ligand AGN-PC-08WSLM family 5 22
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 1
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 1... 1 0
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Gonadotropin-releasing hormone receptor ligand AGN-PC-074DFG f... 2 1
Nuclear receptor ROR-gamma and Prelamin-A/C ligand ST50133141 ... 1 0
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RCV family 2 1
Ribosyldihydronicotinamide dehydrogenase [quinone] and NAD(P)H... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00285632 CHEMBL124254 Bioactive NSC-637993
CFAMM00285624 DNC010752 Investigative Drug NSC-637993
CFAMM00285623 DNC010756 Investigative Drug NSC-645812
CFAMM00285627 DNC010762 Investigative Drug NSC-660838

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26239 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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