CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID318
Family Name Vasopeptidase Inhibitor Fasidotril Family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00187137 Functional Category Investigative Drug with Natural Product
Superfamily Dopamine receptor Ligand Docarpamine Superfamily
Class Class 725

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Plasmepsin-2 Inhibitor KNI-727 Family 3 37
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Tubulin beta chain Inhibitor 6-ile-ustiloxin Family 4 3
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Transient receptor potential cation channel subfamily V member... 3 18
Neprilysin inhibitor SureCN389939 family 5 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[4-(ben... 12 20
Integrin beta-1 and Integrin alpha-4 inhibitor AGN-PC-074GDW f... 9 2
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-ethy... 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(4S)-3... 3 24
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2R)-3-[4-(2-me... 18 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2-me... 4 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN6429531 f... 2 0
Neprilysin inhibitor benzyl (2S)-3-(4-hydroxyphenyl)-2-[[2-(su... 1 1
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Glutamate carboxypeptidase 2 inhibitor 2-(4-hydroxy-3-methoxyp... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00187138 CHEMBL11620 Bioactive AGN-PC-0745FY
CFAMM00187143 CHEMBL325055 Bioactive FASIDOTRILAT
CFAMM00187137 DNC000639 Investigative Drug Fasidotril

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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