CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3208
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(n-oxide-2-pyridylthio)pyridine-3-sulfonamide Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00286327 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 1 Binder Superfamily 4
Class Class 2674

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 22
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(met... 4 15
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(cya... 4 4
Prostaglandin G/H synthase 1 Inhibitor 1-(4-aminosulfonylpheny... 3 18
Prostaglandin G/H synthase 2 Inhibitor 1-(4-(methylsulfonyl)ph... 1 2
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor AGN-P... 1 1
Cannabinoid receptor 2 ligand 1,1,1-trifluoro-N-[(1R)-1-[4-[1-... 2 1
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-050UV6 family 2 2
Cannabinoid receptor 1 ligand SureCN13343196 family 3 3
Cannabinoid receptor 2 and Cytochrome P450 2C9 ligand AGN-PC-0... 1 0
Nuclear receptor ROR-gamma and Prelamin-A/C ligand 13463-41-7 ... 1 7
Metabotropic glutamate receptor 5 and Cytochrome P450 1A2 liga... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00286322 CHEMBL1095884 Bioactive AGN-PC-07ZVPZ
CFAMM00286312 DNC010956 Investigative Drug 4,4'-thiodipyridine-3-sulfonamide
CFAMM00286327 DNC010940 Investigative Drug 4-(N-Oxide-2-pyridylthio)pyridine-3-sulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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