CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3217
Family Name MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-tolylcarbamoyl)benzamide Family
No. of Seeds 6 No. of Other Members 28
Family Centroid CFAMM00286530 Functional Category Investigative Drug
Superfamily Retinoic acid receptor RXR-alpha and MO15-related protein kinase Pfmrk Binder Superfamily
Class Class 1913

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Motilin receptor Ligand GSK962040 Family 30 457
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Peroxisome proliferator-activated receptor gamma and Retinoic ... 4 9
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Transient receptor potential cation channel subfamily V member... 1 5
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Phospholipase D1 Inhibitor Halopemide Family 17 111
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(2,4... 3 6
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Metabotropic glutamate receptor 5 Ligand N-(3-acetamidophenyl)... 4 20
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 0
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 5 8
Vasopressin V1a receptor and Vasopressin V2 receptor ligand CH... 3 5
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Vasopressin V2 receptor ligand [2-chloro-4-(prop-2-enylamino)p... 3 14
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 4
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 3
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Cellular tumor antigen p53 and Inositol monophosphatase 1 inhi... 1 12
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 4 19
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 6
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 3
Inosine-5'-monophosphate dehydrogenase inhibitor 2-chloro-5-[2... 3 0
Inosine-5'-monophosphate dehydrogenase inhibitor 1-[4-chloro-3... 3 5
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 5 1
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 3 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 8
Protoporphyrinogen oxidase inhibitor 2-chloro-N-[[2-chloro-5-(... 1 5
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Vasopressin V2 receptor and Vasopressin V1a receptor ligand (2... 4 0
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 4 6
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 1 5
Tubulin beta-2B chain and Similar to alpha-tubulin isoform 1 i... 1 0
Poly [ADP-ribose] polymerase 2 and Poly [ADP-ribose] polymeras... 1 0
G protein-activated inward rectifier potassium channel 4 and G... 1 0
1-benzoyl-6-chloro-2H-naphtho[1,2,3-de]quinoline-2,7(3H)-dione... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00286511 CHEMBL182687 Bioactive 5-chloro-3-hydroxy-1H-quinazoline-2,4-dione
CFAMM00286501 CHEMBL2178656 Bioactive 2-chloro-N,N-dimethyl-5-[2-(3-prop-1-en-2-ylphenyl)propan-2-ylcarbamoylamino]benzamide
CFAMM00286500 CHEMBL2178654 Bioactive 2-chloro-5-[2-(3-prop-1-en-2-ylphenyl)propan-2-ylcarbamoylamino]benzamide
CFAMM00286499 CHEMBL2178655 Bioactive 2-chloro-N-methyl-5-[2-(3-prop-1-en-2-ylphenyl)propan-2-ylcarbamoylamino]benzamide
CFAMM00286528 CHEMBL2178632 Bioactive 2-chloro-5-[2-(3-phenylphenyl)propan-2-ylcarbamoylamino]benzamide
CFAMM00286530 DNC010968 Investigative Drug 2-chloro-N-(o-tolylcarbamoyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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