CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3221
Family Name Aromatase Inhibitor 2,3,4-trimethoxy-4'-amino-trans-stilbene Family
No. of Seeds 9 No. of Other Members 14
Family Centroid CFAMM00286575 Functional Category Investigative Drug with Natural Product
Superfamily Aromatase and Tubulin beta chain Binder Superfamily
Class Class 2358

Cousin Family NamesSeedsMembers
D(3) dopamine receptor Ligand U-99194A Family 7 33
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Coagulation factor VII and Coagulation factor X Inhibitor 4-(4... 2 12
Tubulin beta chain Inhibitor 2'-amino-3,4,4',5-tetramethoxy-(z... 2 8
Tubulin beta chain Inhibitor 2-amino-3,4',5-trimethoxy-(z)-sti... 1 0
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 2-(4-a... 3 4
Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family 5 12
Aromatase Inhibitor 3,5-diacetoxy-4'-amino-trans-stilbene Family 1 1
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
Sodium-dependent serotonin transporter inhibitor 2-[2-[(dimeth... 3 3
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 1 3
5-hydroxytryptamine receptor 7 and Alpha-2C adrenergic recepto... 3 0
Cannabinoid receptor 1 ligand 6-[(6aR,10aR)-1-hydroxy-6,6,9-tr... 2 1
Kinesin-like protein KIF11 inhibitor SureCN3968042 family 1 3


External ID

Functional Category

Molecule Name

CFAMM00286574 DNC010982 Investigative Drug 3,4,5-Trimethoxy-4'-amino-trans-stilbene
CFAMM00286556 DNC010976 Investigative Drug 2,4-Dimethoxy-4'-amino-trans-stilbene
CFAMM00286573 DNC010981 Investigative Drug 3,4,5-Trimethoxy-3'-amino-trans-stilbene
CFAMM00286555 DNC010977 Investigative Drug 2,4-Dimethoxy-3'-amino-trans-stilbene
CFAMM00286572 DNC010987 Investigative Drug 4-(3,5-Dimethoxyphenethyl)benzenamine
CFAMM00286554 DNC010975 Investigative Drug 3,5-Dimethoxy-4'-amino-trans-stilbene
CFAMM00286571 DNC010984 Investigative Drug 2,3,5-Trimethoxy-4'-amino-trans-stilbene
CFAMM00286570 DNC010989 Investigative Drug 4-(3,4,5-Trimethoxyphenethyl)aniline
CFAMM00286575 DNC010983 Investigative Drug 2,3,4-Trimethoxy-4'-amino-trans-stilbene

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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