CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID3222
Family Name Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00286579 Functional Category Investigative Drug with Natural Product
Superfamily Aromatase and Tubulin beta chain Binder Superfamily
Class Class 2358

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
D(3) dopamine receptor Ligand U-99194A Family 7 33
Bcl-2 Inhibitor family 1 11
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Coagulation factor VII and Coagulation factor X Inhibitor 4-(4... 2 12
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Tubulin beta chain Inhibitor 2'-amino-3,4,4',5-tetramethoxy-(z... 2 8
Tubulin beta chain Inhibitor 2-amino-3,4',5-trimethoxy-(z)-sti... 1 0
Kinesin-like protein KIF11 Inhibitor N-[4-(1,3-benzodioxol-5-y... 1 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4'-am... 3 17
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 7 18
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 2-(4-a... 3 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 3 4
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-aminonaphthalen-1-ol... 2 34
Aromatase Inhibitor 2,3,4-trimethoxy-4'-amino-trans-stilbene F... 9 14
Aromatase Inhibitor 3,5-diacetoxy-4'-amino-trans-stilbene Family 1 1
Tubulin beta chain Inhibitor Colchinol Family 3 109
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
Fatty-acid amide hydrolase 1 Inhibitor 4-nitrophenyl 4-benzylp... 5 35
Carbonic anhydrase 12 and Probable transmembrane carbonic anhy... 2 0
Sodium-dependent serotonin transporter inhibitor 2-[2-[(dimeth... 3 3
Kinesin-like protein KIF11 inhibitor SureCN3968042 family 1 3
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-075CPV ... 2 3


External ID

Functional Category

Molecule Name

CFAMM00286591 DNC010986 Investigative Drug 3-Methoxyl-4'-amino-trans-stilbene
CFAMM00286590 DNC010988 Investigative Drug 4-(3,4-Dimethoxyphenethyl)aniline
CFAMM00286580 DNC010978 Investigative Drug 2,5-Dimethoxy-4'-amino-trans-stilbene
CFAMM00286579 DNC010979 Investigative Drug 2,3-Dimethoxy-4'-amino-trans-stilbene
CFAMM00286592 DNC010980 Investigative Drug 3,4-Dimethoxy-4'-amino-trans-stilbene

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



80838 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543